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5-Methylcoumarin derivatives from Aphyllocladus denticulatus
(1988)
The aerial parts of Aphyllocladus denticulatus afforded, in addition to some widespread compounds, six 5-methylcoumarin derivatives isolated previo. © 1988.
Solution Thermodynamics of 6-Methylcoumarin in Aqueous Media at Several pH Values
(Colegio Farmaceuticos Provincia de Buenos Aires, 2013-04)
Based on van’t Hoff and Gibbs equations, thermodynamic functions Gibbs energy, enthalpy, and entropy of solution and mixing of 6-methylcoumarin in water at pH 1.2, 6.8, and 7.4, were evaluated from solubility values ...
3-Arylcoumarins as highly potent and selective monoamine oxidase B inhibitors: Which chemical features matter?
(Academic Press Inc., 2020)
In vitro intestinal permeability studies, pharmacokinetics and tissue distribution of 6-methylcoumarin after oral and intraperitoneal administration in Wistar rats
(Universidade de São Paulo, 2017-04-20)
6-Methylcoumarin (6MC) is a semisynthetic coumarin with important in vitro and in vivo anti-inflammatory activity. In order to continue the pre-clinical characterization of this molecule, in vitro intestinal permeability, ...
Highly oxygenated sesquiterpenes from Polyachyrus sphaerocephalus and further constituents from chilean mutisieae
(1991)
The aerial parts of Polyachyrus sphaerocephalus gave seven new eudesmane derivatives and a germacra-dien-diol while a reinvestigation of P. fuscus afforded a new caryophyllene, two nerolidolglycosides, a curcumene and two ...
Targeting α -(1,4)-glucosidase in diabetes mellitus type 2: The role of new synthetic coumarins as potent inhibitors
(Bentham Science Publishers B.V., 2018)
Development of a dissolution method based on lipase for preclinical level A IVIVC of oral poly(ε-caprolactone) microspheres
(Editions Sante, 2019-08)
Level A in vitro/in vivo correlation (IVIVC) of poly (ε-caprolactone) (PCL) microspheres for oral administration is challenging since in vitro PCL dissolution takes longer. The aims of this study were: 1) to develop three ...
Molecular structure, experimental and theoretical 1H and 13C NMR chemical shift assignment of cyclic and acyclic α,β-unsaturated esters
(John Wiley & Sons Ltd, 2014-01)
The experimental 1H and 13C NMR spectra of 13 phenyl cinnamates and four 4-methylcoumarins were investigated and their chemical shifts assigned on the basis of the two-dimensional spectra. For the unsubstituted cinnamic ...