Buscar
Mostrando ítems 1-10 de 18
Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism
(WILEY-BLACKWELL, 2012)
Background Mercaptopurine and azathioprine (AZA) are efficacious in treating IBD. 6-tioguanine (6-TGN) levels correlate with therapeutic efficacy, whereas high 6-methylmercaptopurine (6-MMP) levels are associated with ...
Aparecimento de psoríase durante o tratamento das doenças inflamatórias intestinais com infliximabe: A terapia biológica deve ser suspensa?
(2012-04-01)
Context - Several paradoxical cases of infliximab-induced or-exacerbated psoriatic lesions have been described in the recent years. There is disagreement regarding the need to discontinue infliximab in order to achieve the ...
Aparecimento de psoríase durante o tratamento das doenças inflamatórias intestinais com infliximabe: A terapia biológica deve ser suspensa?
(2012-04-01)
Context - Several paradoxical cases of infliximab-induced or-exacerbated psoriatic lesions have been described in the recent years. There is disagreement regarding the need to discontinue infliximab in order to achieve the ...
Immunomodulatory effects of low dose chemotherapy and perspectives of its combination with immunotherapy
(2013-06-01)
Given that cancer is one of the main causes of death worldwide, many efforts have been directed toward discovering new treatments and approaches to cure or control this group of diseases. Chemotherapy is the main treatment ...
Immunomodulatory effects of low dose chemotherapy and perspectives of its combination with immunotherapy
(2013-06-01)
Given that cancer is one of the main causes of death worldwide, many efforts have been directed toward discovering new treatments and approaches to cure or control this group of diseases. Chemotherapy is the main treatment ...
Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis
(Elsevier Masson s.r.l., 2020-10-28)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with no known cure. Aggregates of the nuclear protein TDP-43 have been recognized as a hallmark of proteinopathy in both familial and sporadic cases ...
Fatores associados à qualidade do atendimento a pacientes com doenças inflamatórias intestinais, sob a ótica médica especializada
(Universidade Estadual Paulista (Unesp), 2022-08-02)
Introdução: As doenças inflamatórias intestinais (DII) são afecções inflamatórias crônicas de caráter recorrente, cujas taxas de incidência e prevalência têm aumentado mundialmente, inclusive no Brasil, com importante ...