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Chiral HPLC analysis of donepezil, 5-O-desmethyl donepezil and 6-O-desmethyl donepezil in culture medium: application to fungal biotransformation studies

Barth, Thiago; Conti, Raphael; Pupo, Monica Tallarico; Okano, Laura Tiemi; Bonato, Pierina Sueli (SPRINGER HEIDELBERGHEIDELBERG, 2012)

An high performance liquid chromatography (HPLC) method for the enantioselective determination of donepezil (DPZ), 5-O-desmethyl donepezil (5-ODD), and 6-O-desmethyl donepezil (6-ODD) in Czapek culture medium to be applied ...