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Stability of XIST repression in relation to genomic imprinting following global genome demethylation in a human cell line
(Ribeirão Preto, 2014)
DNA methylation is essential in X chromosome inactivation and genomic imprinting, maintaining repression of XIST in the active X chromosome and monoallelic repression of imprinted genes. Disruption of the DNA methyltransferase ...
Efeitos epigenéticos sobre a diferenciação in vitro de mioblastos e a expressão dos genes CAST e CAPN1 em bovinos
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Genética Evolutiva e Biologia Molecular - PPGGEv, 2013-09-20)
Epigenetics can be defined as the study of heritable changes in phenotype without the occurrence of changes in nucleotide sequence. Epigenetic modifications occur by the chemical changes in DNA and their associated proteins, ...
Efeito do modelador epigenético 5-Aza-2’-Deoxycytidine no desenvolvimento dos embriões bovinos produzidos após choque térmico em oócitos
(Universidade Federal de Juiz de ForaBrasilICB – Instituto de Ciências BiológicasPrograma de Pós-graduação em Ciências Biológicas: Imunologia e Doenças Infecto-Parasitárias/Genética e BiotecnologiaUFJF, 2015)
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
(Biomed Central Ltd., 2009-07-10)
The dose-delivery schedule of conventional chemotherapy, which determines its efficacy and toxicity, is based on the maximum tolerated dose. This strategy has lead to cure and disease control in a significant number of ...
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
(Biomed Central Ltd., 2009-07-10)
The dose-delivery schedule of conventional chemotherapy, which determines its efficacy and toxicity, is based on the maximum tolerated dose. This strategy has lead to cure and disease control in a significant number of ...
Myogenic Differentiation Potential of Mesenchymal Stem Cells Derived from Fetal Bovine Bone Marrow
(Taylor & Francis Inc, 2018-01-01)
The myogenic potential of bovine fetal MSC (bfMSC) derived from bone marrow (BM) remains unknown; despite its potential application for the study of myogenesis and its implications for livestock production. In the present ...
Immunomodulatory effects of low dose chemotherapy and perspectives of its combination with immunotherapy
(2013-06-01)
Given that cancer is one of the main causes of death worldwide, many efforts have been directed toward discovering new treatments and approaches to cure or control this group of diseases. Chemotherapy is the main treatment ...