Buscar
Mostrando ítems 1-10 de 273
Colombian Trypanosoma cruzi major genotypes circulating in patients: Minicircle homologies by cross-hybridization analysis
(2010)
Here we present compelling evidence of Trypanosoma cruzi genotypes infecting 77 human cases of Chagas disease in Santander Department of Colombia. The patients were clinically studied and classified according to the presence ...
Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients
(2022-04-01)
MicroRNAs (miRNAs) are small non-coding RNAs (sRNA), that alter gene expression by binding to target messenger RNAs (mRNAs) and repressing translation. Dysregulated miRNA expression has been implicated in the pathogenesis ...
Small RNA expression profiling reveals hsa-miR-181d-5p downregulation associated with TNF-α overexpression in Sjögren’s syndrome patients
(Frontiers Media, 2022)
MicroRNAs (miRNAs) are small non-coding RNAs (sRNA), that alter gene expression by binding to target messenger RNAs (mRNAs) and repressing translation. Dysregulated miRNA expression has been implicated in the pathogenesis ...
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
(2012)
Adaptation to endoplasmic reticulum (ER) stress depends on the activation of the unfolded protein response (UPR) stress sensor inositol-requiring enzyme 1α(IRE1α), which functions as an endoribonuclease that splices the ...
Orange Juice Attenuates Circulating miR-150-5p, miR-25-3p, and miR-451a in Healthy Smokers: A Randomized Crossover Study
(2021-12-24)
Introduction: Tobacco smoke is associated with oxidative and inflammatory pathways, increasing the risk of chronic-degenerative diseases. Our goal was to evaluate the effects of acute “Pera” and “Moro” orange juice consumption ...
Alpha-glucosidase promotes hemozoin formation in a blood-sucking bug: An evolutionary history
(2009-09-09)
Background: Hematophagous insects digest large amounts of host hemoglobin and release heme inside their guts. In Rhodnius prolixus, hemoglobin-derived heme is detoxified by biomineralization, forming hemozoin (Hz). Recently, ...
Triclosan inhibits tumor necrosis factor-α-stimulated urokinase production in human gingival fibroblasts
(2009)
Background and Objectives: Destruction of the supporting periodontal tissues is
mediated by the action of several proteolytic enzymes. Urokinase is a serine
protease that plays a key role in connective tissue destruction ...
Participación de la autofagia en la inducción del fenotipo sintético por TNF-[alfa] en células musculares lisas vasculares
(Universidad de Chile, 2016)
Antecedentes y objetivo: La aterosclerosis se caracteriza por una desdiferenciación las células de músculo liso vascular (VSMC) a un fenotipo migratorio, proliferativo, con baja expresión de proteínas de contracción y una ...
Effect of Panax ginseng on cytokine expression in bovine mammary glands at drying off
(Elsevier Science, 2010-12)
Biological response modifiers (BRM) are agents that modify the host's response to pathogens with resultant beneficial prophylactic or therapeutic effects. The objectives of this study were to describe the immunomodulatory ...