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Human 14-3-3 Paralogs Differences Uncovered by CrossTalk of Phosphorylation and Lysine Acetylation
(Public Library Science, 2013-02-13)
The 14-3-3 protein family interacts with more than 700 different proteins in mammals, in part as a result of its specific phospho-serine/phospho-threonine binding activity. Upon binding to 14-3-3, the stability, ...
The discovery of Foxl2 paralogs in chondrichthyan, coelacanth and tetrapod genomes reveals an ancient duplication in vertebrates
(2013-07-01)
The Foxl2 (forkhead box L2) gene is an important member of the forkhead domain family, primarily responsible for the development of ovaries during female sex differentiation. The evolutionary studies conducted previously ...
Evidence of functional divergence in MSP7 paralogous proteins : a molecular-evolutionary and phylogenetic analysis
(2016)
Background: The merozoite surface protein 7 (MSP7) is a Plasmodium protein which is involved in parasite invasion; the gene encoding it belongs to a multigene family. It has been proposed that MSP7 paralogues seem to be ...
Differential expression and accumulation of 14-3-3 paralogs in 3T3-L1 preadipocytes and differentiated cells
(Elsevier B.V., 2016-09)
The 14-3-3 protein family interacts with more than 2000 different proteins in mammals, as a result of its specific phospho-serine/phospho-threonine binding activity. Seven paralogs are strictly conserved in mammalian ...
The small rna ryhb homologs from salmonella typhimurium restrain the intracellular growth and modulate the spi-1 gene expression within raw264.7 macrophages
(MDPI AG, 2021-03)
Growing evidence indicates that small noncoding RNAs (sRNAs) play important regulatory roles during bacterial infection. In Salmonella Typhimurium, several sRNAs are strongly up-regulated within macrophages, but little is ...
Evolution and genomic organization of muscle microRNAs in fish genomes
(Biomed Central Ltd, 2014-09-25)
Background: MicroRNAs (miRNAs) are small non-coding RNA molecules with an important role upon post-transcriptional regulation. These molecules have been shown essential for several cellular processes in vertebrates, including ...
Adhesive properties of YapV and paralogous autotransporter proteins of Yersinia pestis
(American Society For Microbiology, 2015-05)
Yersinia pestis is the causative agent of plague. This bacterium evolved from an ancestral enteroinvasive Yersinia pseudotuberculosis strain by gene loss and acquisition of new genes, allowing it to use fleas as transmission ...
Multiple isoforms for the catalytic subunit of PKA in the basal fungal lineage Mucor circinelloides
(Elsevier, 2016-12)
Protein kinase A (PKA) activity is involved in dimorphism of the basal fungal lineage Mucor. From the recently sequenced genome of Mucor circinelloides we could predict ten catalytic subunits of PKA. From sequence alignment ...
Evolution and genomic organization of muscle microRNAs in fish genomes
(Biomed Central Ltd, 2015)