Buscar
Mostrando ítems 1-10 de 473
Streamlined computational pipeline for genetic background characterization of genetically engineered mice based on next generation sequencing data
(2019)
Background: Genetically engineered mice (GEM) are essential tools for understanding gene function and disease modeling. Historically, gene targeting was first done in embryonic stem cells (ESCs) derived from the 129 family ...
Influence of Genetic Background on Fluoride Metabolism in Mice
(SAGE PUBLICATIONS INC, 2009)
A/J and 129P3/J mouse strains have different susceptibilities to dental fluorosis, due to their genetic backgrounds. This study tested whether these differences are due to variations in water intake and/or F metabolism. ...
Effect of ligands to toll-like receptors (TLR) 3, 7 and 9 on mice infected with mouse hepatitis virus A59
(Scientific Research Publishing, 2014-12)
Mice infected with mouse hepatitis virus A59 (MHV-A59), an enveloped, positive-strand RNA Co-ronavirus, induce hepatitis, thymus involution, IgG2a-restricted hypergammaglobulinaemia, transaminase release and autoantibodies ...
Omega-3 Improves Myoblast Transplantation And Modulates Notch And Wnt Signaling In The Mdx Mouse Model Of Dmd
(Pergamon-Elsevier Science LTDOxford, 2016)
Smoking exacerbates amyloid pathology in a mouse model of alzheimers disease
(NATURE PUBLISHING GROUP, 2013)
A new mouse model for Marfan Syndrome presents phenotypic variability associated with the genetic background and overall levels of Fbn1 expression
(San Francisco, 2010)
Marfan syndrome is an autosomal dominant disease of connective tissue caused by mutations in the fibrillin-1 encoding gene FBN1. Patients present cardiovascular, ocular and skeletal manifestations, and although being fully ...
A New Mouse Model for Marfan Syndrome Presents Phenotypic Variability Associated with the Genetic Background and Overall Levels of Fbn1 Expression
(PUBLIC LIBRARY SCIENCE, 2010)
Marfan syndrome is an autosomal dominant disease of connective tissue caused by mutations in the fibrillin-1 encoding gene FBN1. Patients present cardiovascular, ocular and skeletal manifestations, and although being fully ...