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Extracellular matrix stiffness and Wnt/β-catenin signaling in physiology and disease
(NLM (Medline), 2020)
In silico development of a scFv antagonistic to α4β1 integrin
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Recruitment of integrin α ν β 3 to integrin α 5 β 1 -induced clusters enables focal adhesion maturation and cell spreading
(Company of Biologists, 2019-11)
The major fibronectin (FN)-binding α5β1 and αvβ3 integrins exhibit cooperativity during cell adhesion, migration and mechanosensing, through mechanisms that are not yet fully resolved. Exploiting mechanically tunable ...
Substrate engagement of integrins α5 β1 and αv β3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin
(Nature Publishing Group, 2016-03)
The interplay between specific integrin-mediated matrix adhesion and directional persistence in cell migration is not well understood. Here, we characterized fibroblast adhesion and migration on the extracellular matrix ...
Beta 1 integrin predicts survival in breast cancer: a clinicopathological and immunohistochemical study
(LONDON, 2012-08-16)
Abstract
Background
The main focus of several studies concerned with cancer progression and metastasis is to analyze the ...
Kinesin KIF4A transports integrin β1 in developing axons of cortical neurons
(Academic Press Inc Elsevier Science, 2014-09)
CNS axons have poor regenerative ability compared to PNS axons, and mature axons regenerate less well than immature embryonic axons. The loss of regenerative ability with maturity is accompanied by the setting up of a ...
Signaling triggered by Thy-1 interaction with β3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function
(2002)
Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such prevalence, Thy-1 function remains largely obscure in the absence of a defined ligand. Recently described evidence that Thy-1 interacts with β3 integrin ...
Generation of a scFv antagonistic to VLA-4 integrin as potential therapeutic target in muscular dystrophies: in silico phase
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)