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Inclusion Complexes of Cyclodextrins with Galangin: a Thermodynamic and Reactivity Study
(SPRINGER/PLENUM PUBLISHERS, 2010-10)
The formation of the complexes of galangin (GAL) with native β-cyclodextrin
(βCD), and with its substituted counterparts such as dimethyl-βCD (DMβCD) and
hydroxypropyl-βCD (HPβCD), was studied by fluorescence spectra in ...
Effect of PEG-induced molecular crowding on β-Gal thermal stability
(Sociedad Argentina de Biofísica, 2019)
The yeast β-galactosidase or lactase [EC 3.2.1.23] (β-Gal) is a soluble enzyme capable of catalyzing lactose hydrolysis into its constitutive monosaccharides: glucose and galactose. This enzyme has a commercial application ...
An acetylation site in lectin domain modulates the biological activity of polypeptide GalNAc-transferase-2
(De Gruyter, 2012-12)
Polypeptide GalNAc-transferases (ppGalNAc-Ts) are a family of enzymes that catalyze the initiation of mucintype O -glycosylation. All ppGalNAc-T family members contain a common (QXW) 3 motif, which is present in the R-type ...
β-sheet to α-helix conversion and thermal stability of β-Galactosidase encapsulated in a nanoporous silica gel
(Academic Press Inc Elsevier Science, 2019-01-01)
The effect on protein conformation and thermal stability was studied for β-Galactosidase (β-Gal) encapsulated in the nanopores of a silicate matrix (Eβ-Gal). Circular dichroism spectra showed that, compared with the enzyme ...
Binding kinetics between soluble beta-Gal and anti-beta-Gal immobilized on chemically nanopatterned surfaces with fractal topography
(2014)
The present work was aimed at providing experimental support to the correlation
between topographic and kinetic dimensions of protein function we described
previously. Through electronic and colloidal nanolithographic ...
Production, recovery and purification of a recombinant β-galactosidase by expanded bed anion exchange adsorption
(Elsevier Science, 2012-07)
β-Galactosidase is a hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides; its major application in the food industry is to reduce the content of lactose in lactic products. The aim of this ...
GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies
(2019-11-01)
Galectin-8 (Gal-8) is a glycan-binding protein that modulates a variety of cellular processes interacting with cell surface glycoproteins. Neutralizing anti-Gal-8 antibodies that block Gal-8 functions have been described ...
Integrative view of α2,3-sialyltransferases (ST3Gal) molecular and functional evolution in deuterostomes: significance of lineage-specific losses
(Oxford University Press, 2014-12)
Sialyltransferases are responsible for the synthesis of a diverse range of sialoglycoconjugates predicted to be pivotal to deuterostomes' evolution. In this work, we reconstructed the evolutionary history of the metazoan ...
Papel das Galectinas-1, -3 e -9 em doenças inflamatórias crônicas da pele.
(Universidade Estadual Paulista (Unesp), 2021-09-01)
As respostas imunes que envolvem as inflamações crônicas da pele, tais como psoríase e dermatite, são complexas e evidenciam o desafio no diagnóstico clínico, sendo fundamental o estudo de biomarcadores para melhor definição ...
Galectin-1 facilitates macrophage reprogramming and resolution of inflammation through IFN-beta
(Frontiers Media S.A., 2020-06)
During the resolution of acute inflammation, macrophages undergo reprogramming from pro-inflammatory, to anti-inflammatory/reparative, and eventually to pro-resolving macrophages. Galectin-1 (Gal-1) is a bona fide pro-resolving ...