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Palmitoylethanolamide prevents neuroinflammation, reduces astrogliosis and preserves recognition and spatial memory following induction of neonatal anoxia-ischemia
(Springer, 2018-10)
Rational: Neonatal anoxia-ischemia (AI) particularly affects the central nervous system. Despite the many treatments that have been tested, none of them has proven to be completely successful. Palmitoylethanolamide (PEA) ...
Activation of peroxisome proliferator nuclear receptors regulates lipid metabolism in the placenta
(Galenos Yayincilik, 2007-09)
OBJECTIVE: Peroxisome proliferator activated receptors (PPARs), known regulators of lipid homeostasis in different tissues, are crucial during placental development. In this work we aim to determine whether PPARs activation ...
Effects of PPAR activation in the placenta and the fetus: implications in maternal diabetes
(Elsevier, 2011-03)
Peroxisome proliferator-activated receptors (PPARα, PPARδ and PPARγ) are ligand-activated transcription factors that regulate metabolic, anti-inflammatory and developmental processes. The maternal and fetal metabolic ...
Síntese de derivados do cardanol e avaliação sobre receptores ativados por proliferadores peroxissomais
(2018-12-12)
A modulação da expressão de Receptores Ativados por Proliferadores Peroxissomais (PPAR) está implicada em diversas patologias metabólicas e constitui importante alvo de pesquisas de interesse terapêutico. A ativação de ...
Bacupari peel extracts (Garcinia brasiliensis) reduces the biometry, lipogenesis and hepatic steatosis in obese rats
(Food Research International, 2019)
Efeito do chá de folhas de manga (Mangifera indica L.) no estresse oxidativo, na inflamação, na esteatose hepática e na função endotelial em ratos obesosEffect of mango leaf tea (Mangifera indica L.) in the oxidative stress, inflammation, hepatic steatosis, and endothelial function on obese rats
(Universidade Federal de Viçosa, 2019)
Chronic alcohol intake upregulates hepatic expression of carotenoid cleavage enzymes and PPAR in rats
(2010-10-01)
Excessive and chronic alcohol intake leads to a lower hepatic vitamin A status by interfering with vitamin A metabolism. Dietary provitamin A carotenoids can be converted into vitamin A mainly by carotenoid 15,15′-monooxygenase ...