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Role of neuronal guidance cues in the pathophysiology of obesity: A peripher-al and central overview
(2021-06-01)
Obesity is associated with an exacerbated synthesis and secretion of several molecules, which culmi-nates in chronic low-grade inflammation and insulin resistance. Such conditions affect molecular and physiolog-ical responses ...
Transient receptor potential canonical 3 (TRPC3) channels are required for hypothalamic glucose detection and energy homeostasis
(American Diabetes Association, 2017)
The mediobasal hypothalamus (MBH) contains neurons capable of directly detecting metabolic signals such as glucose to control energy homeostasis. Among them, glucose-excited (GE) neurons increase their electrical activity ...
Metabolic Memory Of ß-cells Controls Insulin Secretion And Is Mediated By Camkii
(Elsevier GmbH, 2014)