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Hiperglicemia materna: efeitos no cuidado materno e no desenvolvimento e comportamento dos descendentes
(Universidade Estadual Paulista (Unesp), 2011-03-31)
The aim of the present study was to evaluate the effect of maternal mild hyperglycemia on maternal behavior, as well as on offspring development, behavior, reproductive function, and development of glucose intolerance in ...
Maternal diabetes mellitus - early consequences for the offspring
(Springer, 2007-01-01)
Although several studies have focused on the effects of nutritional status during intrauterine development, few have addressed the impact of maternal diabetes mellitus on renal function and morphology in the young offspring. ...
L-Arginine supplementation improves insulin sensitivity and beta cell function in the offspring of diabetic rats through AKT and PDX-1 activation
(Elsevier Science Bv, 2016)
Maternal hyperglycemia can result in defects in glucose metabolism and pancreatic beta-cell function in offspring. The purpose of this study was to evaluate the impact of maternal diabetes mellitus on pancreatic islets, ...
Complicaciones materno fetales en gestantes con diabetes pregestacional y diabetes gestacional
(Universidad Nacional de Trujillo, 2020)
Altered FOXO1 activation in the programming of cardiovascular alterations by maternal diabetes
(Elsevier Ireland, 2019-01)
Maternal diabetes programs cardiovascular alterations in the adult offspring but the mechanisms involved remain unclarified. Here, we addresed whether maternal diabetes programs cardiac alterations related to extracellular ...
Maternal diets enriched in olive oil regulate lipid metabolism and levels of PPARs and their coactivators in the fetal liver in a rat model of gestational diabetes mellitus
(Elsevier Science Inc., 2020-04)
In a rat model of gestational diabetes mellitus (GDM) programmed in the offspring of neonatal streptozotocin-induced (nSTZ) diabetic rats, lipids are accumulated in the fetal liver in a sex-dependent way. Here, we evaluated ...
Effect of Ginkgo biloba on the reproductive outcome and oxidative stress biomarkers of streptozotocin-induced diabetic rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 2007-08-01)
The aim of the present study was to evaluate the effect of Ginkgo biloba treatment (EGb 761, 200 mg kg-1 day-1) administered from day 0 to 20 of pregnancy on maternal reproductive performance and on the maternal and fetal ...
Effect of Ginkgo biloba on the reproductive outcome and oxidative stress biomarkers of streptozotocin-induced diabetic rats
(Associação Brasileira de Divulgação Científica (ABRADIC), 2007-08-01)
The aim of the present study was to evaluate the effect of Ginkgo biloba treatment (EGb 761, 200 mg kg-1 day-1) administered from day 0 to 20 of pregnancy on maternal reproductive performance and on the maternal and fetal ...
The modulatory role of cytokines IL-4 and IL-17 in the functional activity of phagocytes in diabetic pregnant women
(2018-01-01)
The study investigated the role of cytokines IL-4 and IL-17 in the modulation of the functional activity of mononuclear phagocytes in diabetic pregnant women with hyperglycemia. Sixty pregnant women were assigned to the ...
Severity of prepregnancy diabetes on the fetal malformations and viability associated with early embryos in rats
(2020-11-01)
Preexisting/pregestational diabetes enhances the risk of birth defects. Several factors have been involved during the implantation process, such as cytokines (granulocyte-macrophage-colony-stimulating factor [GM-CSF]). The ...