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Giant vesicles, laurdan, and two-photon fluorescence microscopy: Evidence of lipid lateral separation in bilayers
(Elsevier Academic Press Inc., 2003-03)
This chapter describes giant vesicles, Laurdan, and two-photon fluorescence microscopy. The combination of Laurdan, giant unilamellar vesicles (GUVs), and two-photon fluorescence microscopy has been extremely useful in ...
Computational predictions on the interactions of parabens with a dipalmitoyl phosphatidylcholine lipid bilayer and the human serum albumin protein
(Open Access Text, 2016-09)
Parabens are esters of para-hydroxybenzoic acid extensively used as preservatives in cosmetics and pharmaceutics. In the recent years their safe use has been questioned, mainly due to their estrogenic activity, their ...
Light scattering on the structural characterization of DMPG vesicles along the bilayer anomalous phase transition
(ELSEVIER IRELAND LTDCLARE, 2012)
Highly charged vesicles of the saturated anionic lipid dimyristoyl phosphatidylglycerol (DMPG) in low ionic strength medium exhibit a very peculiar thermo-structural behavior. Along a wide gel-fluid transition region, DMPG ...
Interaction of gramicidin with DPPC/DODAB bilayer fragments
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The interaction between the antimicrobial peptide gramicidin (Gr) and dipalmitoylphosphatidylcholine (DPPC)/dioctadecyldimethylammonium bromide (DODAB) 1:1 large unilamellar vesicles (LVs) or bilayer fragments (BFs) was ...
Preferential location of prilocaine and etidocaine in phospholipid bilayers: A molecular dynamics study
(Elsevier B.V. Sa, 2009-11-01)
In this work, we report a 20-ns constant pressure molecular dynamics simulation of the uncharged form of two amino-amide local anesthetics (LA). etidocaine and prilocaine, present at 1:3 LA:lipid, molar ratio inside the ...
Study of the effect of Na+ and Ca2+ ion concentration on the structure of an asymmetric DPPC/DPPC+DPPS lipid bilayer by Molecular Dynamics Simulation
(Elsevier Science, 2009-10)
A Molecular Dynamics Simulation study of the steady and dynamic properties of an asymmetric phospholipid bilayer was carried out in the presence of sodium or calcium ions. The asymmetric lipid bilayer was seen to resemble ...
The effect of pH on the lytic activity of a synthetic mastoparan-like peptide in anionic model membranes
(2018-11-01)
Peptide sequences containing acidic and basic residues could potentially have their net charges modulated by bulk pH with a possible influence on their lytic activity in lipid vesicles. The present study reports on a ...
StarD7 behaves as a fusogenic protein in model and cell membrane bilayers
(Elsevier Science, 2012-03-03)
StarD7 is a surface active protein, structurally related with the START lipid transport family. So, the present work was aimed at elucidating a potential mechanism of action for StarD7 that could be related to its interaction ...
Trichogin GA IV Alignment and Oligomerization in Phospholipid Bilayers
(Wiley VCH Verlag, 2019-05)
Trichogin GA IV is a short peptaibol with antimicrobial activity. This uncharged, but amphipathic, sequence is aligned at the membrane interface and undergoes a transition to an aggregated state that inserts more deeply ...