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Studies with neuronal cells: From basic studies of mechanisms of neurotoxicity to the prediction of chemical toxicity
(Pergamon-Elsevier Science Ltd, 2008-08)
Neurotoxicology considers that chemicals perturb neurological functions by interfering with the structure or function of neural pathways, circuits and systems. Using in vitro methods for neurotoxicity studies should include ...
Inhibitory autapse mediates anticipated synchronization between coupled neurons
(American Physical Society, 2019-06)
Two identical autonomous dynamical systems unidirectionally coupled in a sender-receiver configuration can exhibit anticipated synchronization (AS) if the Receiver neuron (R) also receives a delayed negative self-feedback. ...
In vivo optogenetic approach to study neuron-oligodendroglia interactions in mouse pups
(Frontiers Media S.A., 2018)
GABAA receptor and cell membrane potential as functional endpoints in cultured neurons to evaluate chemicals for human acute toxicity
(Pergamon-Elsevier Science Ltd, 2010-02)
Toxicity risk assessment for chemical-induced human health hazards relies mainly on data obtained from animal experimentation, human studies and epidemiology. In vitro testing for acute toxicity based on cytotoxicity assays ...
Gabaergic mechanisms of hypothalamic nuclei in the expression of conditioned fear
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
The amygdala, the dorsal periaqueductal gray (dPAG), and the media] hypothalamus have long been recognized to be a neural system responsible for the generation and elaboration of unconditioned fear in the brain. It is also ...
Impact of chronic transcranial random noise stimulation (tRNS) on GABAergic and glutamatergic activity markers in the prefrontal cortex of juvenile mice
Transcranial random noise stimulation (tRNS), a non-invasive neuromodulatory technique capable of altering cortical activity, has been proposed to improve the signal-to-noise ratio at the neuronal level and the sensitivity ...
Expression and function of non-neuronal GABA transporters in human lymphocytes
(Asian Network for Scientific Information, 2017-01-15)
Background: Neurotransmitters not only play a key role in neuronal communication but also coordinate cell functions in non-neuronal cells, such as immune cells. Previous research reported a complete GABAergic system in ...
GABAergic Regulation of Astroglial Gliotransmission through Cx43 Hemichannels
(2022)
Gamma-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain. It is produced by interneurons and recycled by astrocytes. In neurons, GABA activates the influx of Cl- via the GABAA receptor or ...
Circulating ghrelin acts on GABA neurons of the area postrema and mediates gastric emptying in male mice
(Endocrine Society, 2017-05)
Ghrelin is known to act on the area postrema (AP), a sensory circumventricular organ located in the medulla oblongata that regulates a variety of important physiological functions. However, the neuronal targets of ghrelin ...