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Comparative analysis of loss of heterozygosity and microsatellite instability in adult and pediatric melanoma.
(2005)
Although 0.3% of melanomas occur in children, the incidence has risen in past decades. In adult melanoma, some chromosomal regions in 1p, 6q, 9p, 10q, and 11q are frequently deleted. Microsatellite instability (MSI), which ...
Monossomia do cromossomo E3 em felinos FeLV positivos com neoplasias hematopoiéticas
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2017-09-06)
Hematopoietic tumors are the most common neoplastic disorders in felines. Many of these tumors are associated with infection by feline leukemia virus (FeLV) and one of the described mechanisms is the integration of viral ...
Clinical, Cytogenetic and Molecular Study in a Case of r(3) with 3p Deletion and Review of the Literature
(Karger, 2011-01-01)
Ring chromosome 3 is a rare abnormality with only 10 patients described in the literature. We report a patient with r(3) and similar to 6-Mb distal 3p deletion. Single nucleotide polymorphism array, multiplex ligation-dependent ...
Comparison of features of human lung cancer cell lines and their corresponding tumors
(AMER ASSOC CANCER RESEARCH, 1999)
Although human lung tumor-derived cell lines play an important role in the investigation of lung cancer biology and genetics, there is no comprehensive study comparing the genotypic and phenotypic properties of lung cancer ...
The methylating agent streptozotocin induces persistent telomere dysfunction in mammalian cells
(Elsevier Science, 2015-12)
We analyzed chromosomal aberrations involving telomeres in the progeny of mammalian cells exposed to the methylating agent and antineoplastic/diabetogenic drug streptozotocin (STZ), to test whether it induces long-term ...