Buscar
Mostrando ítems 81-90 de 783
ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19
At the end of 2019, the coronavirus disease 2019 (COVID-19), caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in China.
Currently, it is breaking out globally and posing a serious threat ...
Therapeutic utility of glucocorticoids and antihistamines cotreatment. Rationale and perspectives
(Wiley, 2019-12)
Antihistamines and glucocorticoids (GCs) are often used together in the clinic, in several inflammatory-related situations. Even though there is no clear rationale for this drug association, the clinical practice is based ...
Cuff-induced vascular intima thickening is influenced by titration of the Ace gene in mice
(AMER PHYSIOLOGICAL SOC, 2009)
Lacchini S, Heimann AS, Evangelista FS, Cardoso L, Silva GJ, Krieger JE. Cuff-induced vascular intima thickening is influenced by titration of the Ace gene in mice. Physiol Genomics 37: 225-230, 2009. First published March ...
Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors
(Nature Publishing Group, 2005-06-27)
1 Effects of derivatives of coclaurine (C), which mimic the ‘eastern’ or the nonquaternary halves of
the alkaloids tetrandrine or d-tubocurarine, respectively, both of which are inhibitors of nicotinic
acetylcholine ...
SARS-CoV-2 Pathogenesis: Imbalance in the Renin-Angiotensin System Favors Lung Fibrosis
(Frontiers Research Foundation, 2020-06)
After SARS-CoV-2 infection, a major complication of those who survived to COVID-19 outbreak is the development of severe lung disease leading to pulmonary fibrosis. At earliest step of virus-host cell interaction when the ...
Expressao do receptor de transferrina (T9) em portadores de AIDS do grupo III (Linfoadenopatia generalizada persistente): analise imunocitoquimica em aspirado ganglionar
(Universidade Federal de São Paulo (UNIFESP), 1991)
SARS-CoV-2-mediated inflammatory response in lungs: should we look at RAGE?
(Springer, 2020)
The novel coronavirus disease (COVID-19) pandemic is placing significant strains on health systems, scientific communities, essential public services, and economies all over the world. In this context, the world ' s ...
Selection of aptamers which binds human ACE-2 (angiotensin converting enzyme) for blocking RBD (receptor-binding domain) of SARS-CoV-2 protein S
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)
Leaving no stone unturned: Allosteric targeting of SARS-CoV-2 Spike protein at putative druggable sites disrupts human angiotensin-converting enzyme interactions at the receptor binding domain.
The systematic entry of SARS-CoV-2 into host cells, as mediated by its Spike (S) protein, is
highly essential for pathogenicity in humans. Hence, targeting the viral entry mechanisms
remains a major strategy for COVID-19 ...