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Development of a nanostabilized biocatalyst using an extremophilic microorganism for ribavirin biosynthesis
(Elsevier Science, 2015-11)
Ribavirin is a guanosine analogue commonly used as an antiviral compound for the treatment of Hepatitis C virus (HCV) infection. The biosynthesis of this compound using Geobacillus kaustophilus ATCC 8005 as biocatalyst is ...
Flow cytometry based micronucleus assay for evaluation of genotoxic potential of 2-ACBs in hepatic cells HepG2
(Associa????o Brasileira de Energia Nuclear, 2018)
Hepato- and reno-protective effects of synthetic organoselenium compound, binaphthyl diselenide, against chemical-induced oxidative stress
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2010-06-16)
The liver presents extraordinary functional diversity, particularly in the control of energy
production, immune defense and volemic reserve. The human being is exposed
occupationally and in the environment to a variety ...
Atividade antioxidante do e-1,1-metiltio-selenofenil-2-pirrolidinona-hepteno: um composto orgânico de selênio com baixa toxicidade
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2007-04-20)
The objective of this work was to evaluate the antioxidant activity of (E)-1-(1-(methylthio)-1-selenopheny) hept-1-en-2-yl) pyrrolidin-2-one: an organoselenium compound with low toxicity (compound 1). A number of parameters ...
Natural killer cell receptor and HLA-C gene polymorphisms among patients with hepatitis C: a comparison between sustained virological responders and non-responders
(John Wiley & Sons A/S, 2010-04)
Background/Aims: Killer cell immunoglobulin-like receptors (KIR) are
involved in the activation/inhibition of NK cells through an interaction with
HLA class I molecules on target cells. Our study aimed to evaluate ...