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Synthetic fentanyls evaluation and characterization by infrared spectroscopy employing in silico methods
(2021-10-01)
Non-pharmaceutical fentanyls (NPFs) are synthetic substances analogous to fentanyl that have not been approved for medical use. Their clandestine synthesis involves chemical modification of an existing drug, which may cause ...
Estabelecimento de condições para ensaio de dissolução de cápsulas de cinarizina empregando planejamento fatorial
(Sociedade Brasileira de Química, 2011-01-01)
This work describes the establishment of dissolution test conditions for 75 mg cinnarizine capsules using a multivariate approach. A 2³ full factorial design was carried out to achieve the best conditions and HCl 0.1 mol ...
Planejamento de experimentos bayesianos: aplicações em experimentos na presença de tendências lineares
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Estatística - PPGEs, 2007-01-11)
We present a general introduction in the construction of experimental design, spe-
cially a general factorial design and factorial design 2k and some Bayesian criteria in
the construction of experimental design. In ...
Development of Cationic Solid Lipid Nanoparticles with Factorial Design-Based Studies for Topical Administration of Doxorubicin
(AMER SCIENTIFIC PUBLISHERSVALENCIA, 2012)
Topical chemotherapy using doxorubicin, a powerful anticancer drug, can be used as an alternative with reduced systemic toxicity when treating skin cancer. The aim of the present work was to use factorial design-based ...
New factorial designs to evaluate chemisorption of divalent metals on aminated silicas
(Academic Press IncSan DiegoEUA, 2001)
Full factorial design applied to intercalation of amines in lamellar titanium phenylphosphonate and titanium phenylarsonate
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2004)
Factorial design for multivariate optimization of an on-line preconcentration system for platinum determination by ultrasonic nebulization coupled to inductively coupled plasma optical emission spectrometry
(2004)
A system for on-line preconcentration and determination of platinum by ultrasonic nebulization (USN) coupled to inductively coupled plasma optical emission spectrometry (ICP-OES) was studied. It is based on the chemical ...
Optimization of the operating conditions using factorial designs for determination of uranium by inductively coupled plasma optical emission spectrometry
(2011)
A critical evaluation of the determination of uranium by inductively coupled plasma optical emission spectrometry was performed using factorial designs (23) involving the factors: acid concentration, radio frequency power ...
Polymeric nanoparticles loaded with the 3,5,3'-triiodothyroacetic acid (Triac), a thyroid hormone: factorial design, characterization, and release kinetics
(Dove MedicalMacclesfield, 2012-07)
This present investigation deals with the development and optimization of polymeric nanoparticle systems loaded with 3,5,3′-triiodothyroacetic acid (Triac). A '2 POT. 11-6' fractional factorial design and another '2 POT. ...