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Mitochondrial dysfunction and therapeutic approaches in respiratory and limb muscles of cancer cachectic mice
(Wiley, 2013-09)
Abnormalities in mitochondrial content, morphology, and function were reported in several muscle wasting conditions. We specifically explored whether experimental cancer-induced cachexia may alter mitochondrial respiratory ...
Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell
(Springer, 2016)
During the last two decades, new insights into proteasome function and its role in several human diseases made it a potential therapeutic target. In this context, Amblyomin-X is a Kunitz-type FXa inhibitor similar to ...
Neuropatia periférica induzida por quimioterapia: uma revisão integrativa da literatura
(Universidade Federal de Santa MariaBrasilCiências da SaúdeUFSMPrograma de Pós-Graduação em Ciências da SaúdeCentro de Ciências da Saúde, 2021-08-24)
Antineoplastic chemotherapy represents the use of isolated or combined chemical substances in the treatment of malignant tumors, being considered one of the most important ways to fight cancer. Peripheral neuropathy (PN) ...
Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness
(Wiley, 2014-07)
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen ...
-α-synuclein overexpression triggers a lipid metabolic switch: lipid droplets as an early marker of neurodegeneration
(Sociedad Argentina de Investigación en Neurociencias, 2018)
Pathological accumulation of α-synuclein (α-syn) is a hallmark of Parkinson ‘s disease. α-syn is highly expressed in the brain and has the intriguing characteristic of interacting with lipids. However, little is known about ...
Diagnóstico de errores de transcripción detectados en las órdenes de producción de mezclas oncológicas
(Universidad de Ciencias Aplicadas y AmbientalesFacultad de CienciasBogotá, 2014)
Se hizo necesario hacer un diagnóstico para determinar los errores de transcripción más frecuentes en las órdenes de producción de mezclas oncológicas e identificar los profesionales de salud que participan en la generación ...
Factores pronósticos de la supervivencia global y supervivencia libre de progresión en pacientes con mieloma múltiple sometidos a trasplante autólogo de precursores hematopoyéticos en el Hospital Nacional Edgardo Rebagliati Martins
(Universidad Peruana Cayetano HerediaPE, 2019)
El tratamiento de los pacientes con Mieloma Múltiple ha experimentado un cambio dramático en las últimas décadas con el uso de estrategias como drogas inmunomuduladoras e inhibidores de proteosoma, el Trasplante Autólogo ...
Mieloma múltiple
(Universidad de Sonora, 2014)
Effectiveness of Free and Liposome-Entrapped Antitumoral Drugs against Hepatocellular Carcinoma: A Comparative In vitro Study
(AMG Transcend Association, 2023)