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Temporal gene expression in the hippocampus and peripheral organs to endotoxin-induced systemic inflammatory response in caspase-1-deficient mice
Objectives: Caspase-1 (casp1), a key protease involved in the systemic inflammatory response syndrome (SIRS), controls the brain expression of a set of eight genes: Nos2 and Ptgs2 (nitric oxide synthase 2 and prostagland ...
Caracterização ultraestrutural de junções neuromusculares de diafragma de camundongos com disfunção colinérgica
(Universidade Federal de Minas GeraisUFMG, 2014-02-25)
One of the most critical processes of cholinergic transmission involves the event of storage of acetylcholine (ACh) in synaptic vesicles (SVs) through the vesicular acetylcholine transporter (VAChT). To assess the functional ...
Changes in renal WT-1 expression preceding hypertension development
(BioMed Central, 2016-03)
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable ...
Prolonged histamine deficiency in histidine decarboxylase gene knockout mice affects Leydig cell function
(American Society of Andrology, 2007-01)
The present study focuses on histaminergic regulation of Leydig cell physiology, since limited information is available so far. To evaluate the dependency of Leydig cells on histamine (HA), we performed experiments using ...
Patrón génico de fibrosis y apoptosis en nefropatía obstructiva experimental : : modulación por rosuvastatina
(Universidad Nacional de Cuyo. Facultad de Ciencias Médicas, 2010)
Patterns of differential gene expression in adult rotation-resistant and wild-type western corn rootworm digestive tracts
(Wiley Blackwell Publishing, Inc, 2015-07)
The western corn rootworm (WCR, Diabrotica virgifera virgifera LeConte) is an important pest of corn. Annual crop rotation between corn and soybean disrupts the corn‐dependent WCR life cycle and is widely adopted to manage ...
Impact of Heterozygosity for Acid-Labile Subunit (IGFALS) Gene Mutations on Stature: Results from the International Acid-Labile Subunit Consortium
(Endocrine Society, 2010-09)
Context: To date, 16 IGFALS mutations in 21 patients with acid-labile subunit (ALS) deficiency have been reported. The impact of heterozygosity for IGFALS mutations on growth is unknown. Objective: The study evaluates the ...