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Participação do sistema endocanabinoidérgico no mecanismo antinociceptivo da ketamina
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2014-04-03)
The ability to feel pain is essential for maintenance of the life, without her
tissue trauma would not be detected or prevented, causing significant tissue
and nerve damage. The discovery of new analgesic mechanisms ...
Avaliação do efeito antinociceptivo do canabidiol na dor neuropática e mecanismos endógenos envolvidos neste evento
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FARMACOLOGIAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2021-08-18)
Introduction: Cannabidiol (CBD) is the second most abundant pharmacologically active component present in the Cannabis sp. Unlike THC, the main psychoactive component responsible for the signs commonly observed in people ...
Um estudo sobre os mecanismos antinociceptivos periféricos induzidos pela serotonina
(Universidade Federal de Minas GeraisUFMG, 2015-10-13)
Serotonin (5-HT) is a biogenic amine with important functions in the central nervous system, such as behavior, mood, sleep and appetite, and is part of the descending inhibitory pain pathway. So far, only its pro-nociceptive ...
Participação dos sistemas opioidérgico e canabi-noidérgico na modulação endógena periférica da dor inflamatória muscular
(Universidade Federal de Minas GeraisUFMG, 2015-08-28)
Pain processing starts from a noxious stimulus able to sensitize nociceptor peripheral terminals. Pain information converges from the periphery to the dorsal horn of the spi-nal cord through fibers type A, A and C. Once ...
Atividade antinociceptiva dos ácidos epoxieicosatrienoicos (EETs) no modelo de nocicepção periférica em camundongos
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FARMACOLOGIAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2021-12-09)
INTRODUCTION: Epoxyeicosatrienoic acids (EETs) are cytochrome P450-epoxygenase-derived metabolites of arachidonic acid that act as endogenous signaling molecules in multiple biological systems. The major roles of EETs ...
Estudo sobre os mecanismos antinociceptivos periféricos induzidos pela dopamina
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE FARMACOLOGIAPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2020-03-20)
INTRODUCTION: Dopamine (DA) is an abundant neurotransmitter in the Central
Nervous System, exercising cognitive and motor functions, in addition to being
identified as an important agent in the descending inhibitory ...
Absolute geomagnetic paleointensity after the Cretaceous Normal Superchron and just prior to the Cretaceous-Tertiary transition
(2004)
We report a detailed rock magnetic and Thellier paleointensity study from Autlan volcanic succession in western Mexico. The whole rock K-Ar age obtained for these lavas, 67.4 ± 1.2 Ma, together with the magnetostratigraphy ...
Absolute geomagnetic paleointensity after the Cretaceous Normal Superchron and just prior to the Cretaceous-Tertiary transition
(2004)
We report a detailed rock magnetic and Thellier paleointensity study from Autlan volcanic succession in western Mexico. The whole rock K-Ar age obtained for these lavas, 67.4 1.2 Ma, together with the magnetostratigraphy ...
Toward the feldspar alternative for cosmogenic 10Be applications
(ElsevierNL, 2017-06)
The possibility of quantifying surface processes in mafic or volcanic environment using the potentialities offered by the in situ-produced cosmogenic nuclides, and more specifically by the in situ-produced 10Be, is often ...
Participação de canabinóides endógenos, da via NO/cGMP/K+ATP e do sistema noradrenérgico na antinocicepção induzida pelo exercício físico em ratos
(Universidade Federal de Minas GeraisUFMG, 2012-04-16)
The antinociception induced by physical exercise has been widely investigated in the literature since the end of the 1970s. The majority of studies have demonstrated the endogenous opioid system as the main one involved ...