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CD4+FOXP3+cells produce IL-10 in the spleens of dogs with visceral leishmaniasis
(Elsevier B.V., 2014-05-28)
Visceral Leishmaniasis (VL) is caused by intracellular parasites of the genus Leishmania that affect humans and several animal species. Dogs are one of the main urban reservoirs of the parasite and play a central role in ...
Participation of the SMAD2/3 signalling pathway in the down regulation of megalin/LRP2 by transforming growth factor beta (TGF-ss1)
(2019)
Megalin/LRP2 is a receptor that plays important roles in the physiology of several organs, such as kidney, lung, intestine, and gallbladder and also in the physiology of the nervous system. Megalin expression is reduced ...
Expression of matrix metalloproteinases in cyclosporin-treated gingival fibroblasts is regulated by transforming growth factor (TGF)-beta 1 autocrine stimulation
(Amer Acad PeriodontologyChicagoEUA, 2002)
Opposite effects of bFGF and TGF-beta on collagen metabolism by human periodontal ligament fibroblasts
(Elsevier B.V., 2007-08-01)
This study evaluated the effects of bFGF and TGF-beta, individually and combined, on cell proliferation and collagen metabolism. Primary human periodontal ligament cells were stimulated with two concentrations (I and 10 ...
Opposite effects of bFGF and TGF-beta on collagen metabolism by human periodontal ligament fibroblasts
(Elsevier B.V., 2007-08-01)
This study evaluated the effects of bFGF and TGF-beta, individually and combined, on cell proliferation and collagen metabolism. Primary human periodontal ligament cells were stimulated with two concentrations (I and 10 ...
Transforming growth factor beta neutralization reduces Trypanosoma cruzi infection and improves the cardiac performance: in vitro and in vivo assays
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2021)
Influence of the photoperiod on TGF-β1 and p15 expression in hamster Leydig cells
(Inst Animal Reproduction Food Research, 2012-12)
Adult hamsters exposed to short photoperiods show a marked atrophy of their internal reproductive organs, including a reduction in size, though not number of Leydig cells. Transforming growth factor-β1 (TGF-β1) is involved ...
Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway
(JOHN WILEY & SONS LTD, 2009)
Common features such as elastic fibre destruction, mucoid accumulation, and smooth muscle cell apoptosis are co-localized in aneurysms of the ascending aorta of various aetiologies. Recent experimental studies reported an ...
Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo
(Wiley-Blackwell, 2002-11-01)
Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 and in the smad proteins cascade (smad 2/3, smad4, smad7), focusing on megakaryocytes, in the bone marrow irradiated in vivo. ...