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Alternatives for the Treatment of Schistosomiasis: Physico-Chemical Characterization of an Inclusion Complex Between Praziquantel and Hydroxypropyl-beta-Cyclodextrin
(Colegio Farmaceuticos Provincia De Buenos AiresLa PlataArgentina, 2010)
Pharmacokinetics of combined treatment with praziquantel and albendazole in neurocysticercosis
(Wiley, 2011)
Neurocysticercosis is the most common cause of acquired epilepsy in the world. Antiparasitic treatment of viable brain cysts is of clinical benefit, but current antiparasitic regimes provide incomplete parasiticidal efficacy. ...
Improvement of the oral praziquantel anthelmintic effect by cyclodextrin complexation
(Taylor & Francis Ltd, 2010-01-01)
Schistosomiasis is a parasitic disease which kills a half million people per year, a I I over the world. Praziquantel (PZQ) is the drug-of-choice for schistosomiasis because of its effectiveness, ease of administration, ...
Thermal characterization of solid lipid nanoparticles containing praziquantel
(Springer, 2012-04-01)
Solid lipid nanoparticles (SLNs), loaded and unloaded with praziquantel (PRZ-load SLN and PRZ-unload SLN) were prepared by two different procedures: (a) oil-in-water hot microemulsion method, obtaining at 70 degrees C an ...
LC Evaluation of Intestinal Transport of Praziquantel
(Vieweg, 2009-06-01)
Praziquantel (PZQ) is a highly lipophilic drug with low aqueous solubility. Despite this, it is well absorbed from the gastrointestinal tract. In this study, a simple LC method was developed and validated, in order to ...