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Isolation and Characterization of a Natriuretic Peptide from Crotalus oreganus abyssus (Grand Canyon Rattlesnake) and its Effects on Systemic Blood Pressure and Nitrite Levels
(SPRINGER, 2011)
Studies on the therapeutic potential of venom peptides have significantly advanced the development of new peptide drugs. A good example is captopril, a synthetic peptide drug, which acts as an anti-hypertensive and ...
Mechanistic aspects of CPP-mediated intracellular drug delivery: Relevance of CPP self-assembly
(ELSEVIER, 2006-03)
In recent years, cell-penetrating peptides have proven to be an efficient intracellular delivery system. The mechanism for CPP internalisation, which first involves interaction with the extracellular matrix, is followed ...
Amphibian secretions for drug discovery studies: A search for new antiparasitic and antifungal compounds
(2007-01-10)
The antiparasitic and antifungal activities of nine amphibian skin secretions were studied in different in vitro models. Seven secretions presented a considerable antiprotozoan activity and one showed promising results ...
Amphibian secretions for drug discovery studies: A search for new antiparasitic and antifungal compounds
(2007-01-10)
The antiparasitic and antifungal activities of nine amphibian skin secretions were studied in different in vitro models. Seven secretions presented a considerable antiprotozoan activity and one showed promising results ...
An Optimized Protocol for the Synthesis of Peptides Containing trans-Cyclooctene and Bicyclononyne Dienophiles as Useful Multifunctional Bioorthogonal Probes
(Wiley VCH Verlag, 2021-09-09)
Despite the great advances in solid-phase peptide synthesis (SPPS), the incorporation of certain functional groups into peptide sequences is restricted by the compatibility of the building blocks with conditions used during ...
Serological diagnosis of lung cystic hydatid disease using the synthetic p176 peptide
(American Society for Microbiology, 2012)
Cystic hydatid disease (CHD) is a worldwide zoonosis caused by the larval stage of the dog tapeworm Echinococcus granulosus. Diagnosis is based on imagenological tools (abdominal ultrasound, chest X-rays, or computed ...