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CHARMM Force Field Parameterization of Rosiglitazone
(Wiley-blackwellMaldenEUA, 2011)
New recurrent deletions in the PPAR gamma and TP53 genes are associated with childhood myelodysplastic syndrome
(Pergamon-Elsevier B.V. Ltd, 2009-01-01)
Myelodysplastic syndrome (MDS) is a rare hematological malignancy in children. It was performed FISH analysis in 19 pediatric MDS patients to investigate deletions involving the PPAR gamma and TP53 genes. Significant losses ...
New recurrent deletions in the PPAR gamma and TP53 genes are associated with childhood myelodysplastic syndrome
(Pergamon-Elsevier B.V. Ltd, 2009-01-01)
Myelodysplastic syndrome (MDS) is a rare hematological malignancy in children. It was performed FISH analysis in 19 pediatric MDS patients to investigate deletions involving the PPAR gamma and TP53 genes. Significant losses ...
A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis
(2008)
Peroxisome proliferator activated receptors (PPARs, alpha, beta/delta, gamma) control lipid homeostasis and differentiation in various tissues and tumor cells. PPARbeta and PPARgamma increase oligodendrocyte maturation in ...
Low-Resolution Molecular Models Reveal the Oligomeric State of the PPAR and the Conformational Organization of Its Domains in Solution
(Public Library Science, 2012-02-21)
The peroxisome proliferator-activated receptors (PPARs) regulate genes involved in lipid and carbohydrate metabolism, and are targets of drugs approved for human use. Whereas the crystallographic structure of the complex ...
Low-Resolution Molecular Models Reveal the Oligomeric State of the PPAR and the Conformational Organization of Its Domains in Solution
(Public Library Science, 2012-02-21)
The peroxisome proliferator-activated receptors (PPARs) regulate genes involved in lipid and carbohydrate metabolism, and are targets of drugs approved for human use. Whereas the crystallographic structure of the complex ...
Dietary Fatty Acid Quality Affects AR and PPAR gamma Levels and Prostate Growth
(Wiley-lissHobokenEUA, 2009)
Sex-dependent changes in lipid metabolism, PPAR pathways and microRNAs that target PPARs in the fetal liver of rats with gestational diabetes
(Elsevier Ireland, 2018-02)
Gestational diabetes mellitus (GDM) is a prevalent disease that impairs fetal metabolism and development. We have previously characterized a rat model of GDM induced by developmental programming. Here, we analyzed lipid ...
Controle da adipogênese por ácidos graxos
(Sociedade Brasileira de Endocrinologia e Metabologia, 2009)
A obesidade é um dos principais problemas de saúde pública. Indivíduos obesos são mais suscetíveis a desenvolver doenças cardiovasculares e diabetes melito tipo 2. A obesidade resulta do aumento no tamanho e no número de ...