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Interactions between the NO-Citrulline Cycle and Brain-derived Neurotrophic Factor in Differentiation of Neural Stem Cells
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INCBETHESDA, 2012)
The diffusible messenger NO plays multiple roles in neuroprotection, neurodegeneration, and brain plasticity. Argininosuccinate synthase (AS) is a ubiquitous enzyme in mammals and the key enzyme of the NO-citrulline cycle, ...
Schwann-like macroglia in adult rat brain
(2000)
Olfactory ensheathing cells (OECs) share properties with astrocytes and Schwann cells. This study was designed to test the hypothesis that glia with properties similar to those exhibited by OECs might be present in brain ...
Schwann-like macroglia in adult rat brain
(2000)
Olfactory ensheathing cells (OECs) share properties with astrocytes and Schwann cells. This study was designed to test the hypothesis that glia with properties similar to those exhibited by OECs might be present in brain ...
Rol funciónal de la internalización y transporte retrogrado del receptor de neurotrofinas p75 en neuronas simpáticas
(2012)
Las neurotrofinas, entre ellas el factor de crecimiento nervioso (NGF) y el factorneurotrófico derivado del cerebro (BDNF), son factores solubles secretados tanto porneuronas como por los tejidos que son inervados por ellas ...
BDNF isoforms: a round trip ticket between neurogenesis and serotonin?
(Wiley, 2016-07)
The brain-derived neurotrophic factor, BDNF, was discovered more than 30 years ago and, like other members of the neurotrophin family, this neuropeptide is synthetized as a proneurotrophin, the pro-BDNF, which is further ...
Antagonism of proNGF or its receptor p75NTR reverses remodelling and improves bladder function in a mouse model of diabetic voiding dysfunction
(Springer, 2020-09)
Although 80% of diabetic patients will suffer from voiding difficulties and urinary symptoms, defined as diabetic voiding dysfunction (DVD), therapeutic targets and treatment options are limited. We hypothesise that the ...
mechanisms of long-distance control of dendritic growth by brain-derived neurotrophic factor (BDNF) in central neurons
(2019)
Brain Derived Neurotrophic Factor (BDNF) is broadly express in many circuits of the central nervous system (CNS) and binds its receptors TrkB and p75. BDNF triggers different signaling pathways, including the kinases ERK1/2, ...