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Antarctic thraustochytrids as sources of carotenoids and high-value fatty acids
(MDPI, 2021)
Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and carotenoids are needed as
human dietary supplements and are essential components in commercial feeds for the production
of aquacultured seafood. Microorganisms ...
Activity of Fluorine-Containing Analogues of WC-9 and Structurally Related Analogues against Two Intracellular Parasites: Trypanosoma cruzi and Toxoplasma gondii
(Wiley VCH Verlag, 2016-11)
Two obligate intracellular parasites, Trypanosoma cruzi, the agent of Chagas disease, and Toxoplasma gondii, an agent of toxoplasmosis, upregulate the mevalonate pathway of their host cells upon infection, which suggests ...
Estudos da biossíntese das piranocumarinas xantiletina e seselina em laranja pêra (Citrus sinensis (L.) Osbeck) e limão cravo (Citrus limonia Osbeck)
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2017-04-06)
The present work describes the study of biosynthesis of pyranocoumarins in Citrus sinensis and Citrus limonia. Coumarins, like other phenylpropanoids, have biosynthetic origin in p-hydroxy cinnamic acid and their great ...
Short- and long-term effects on reproductive parameters of female Wistar rats after exposure to rosuvastatin starting in pre-puberty
(2020-06-10)
Statins are a class of drugs that act lowering lipid levels by inhibiting cholesterol biosynthesis. Additionally, statins can act by “pleiotropic effects”, related to the inhibition of synthesis of the other mevalonate ...
Saccharomyces cerevisiae como modelo genético para estudo da deficiência da mevalonato quinase (MKD) em humanos
(Universidade Federal de PernambucoUFPEBrasilPrograma de Pos Graduacao em Genetica, 2019)
Analysis of Schistosoma mansoni genes shared with Deuterostomia and with possible roles in host interactions
(2007-11)
Abstract
Background:
Schistosoma mansoni is a blood helminth parasite that causes schistosomiasis, a disease that affects 200 ...
Citrus reticulata peel oil as an antiatherogenic agent: Hypolipogenic effect in hepatic cells, lipid storage decrease in foam cells, and prevention of LDL oxidation
(Elsevier, 2020-08-28)
Background and aims: Hypercholesterolemia and oxidative stress are two of the most important risk factors for atherosclerosis. The aim of the present work was to evaluate mandarin (Citrus reticulata) peel oil (MPO) in ...
Design, characterization and in vitro evaluation of linalool-loaded solid lipid nanoparticles as potent tool in cancer therapy
(Elsevier Science, 2017-03)
Linalool (LN) is a monoterpene found in essential oils of plants and herbs that producesmultiple effects on the mevalonate pathway and interesting antiproliferative activity incancer cells. However, due to its poor aqueous ...