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Modeling the response of Japanese quail hens to lysine intake
(2019-06-01)
Studies on Japanese quails have been conducted using the dose response method over the years and, to date, there have been few studies on the response of quails to the amino acid intake, such as lysine. Thus, the objectives ...
Activation of Ca2+-independent membrane-damaging activity in Lys49-phospholipase A(2) promoted by amphiphilic molecules
(Elsevier B.V., 2004-09-17)
Association of class-II phospholipase A(2) (PLA(2)) with aggregated phospholipid substrate results in elevated levels of the Ca2+-dependent hydrolytic activity. The Asp49 residue participates in coordination of the Ca2+ ...
Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo
(PLoS One 9(10):e109846, 2014-10-07)
Two subtypes of phospholipases A2 (PLA2s) with the ability to induce myonecrosis, ‘Asp49’ and ‘Lys49’ myotoxins, often coexist in viperid snake venoms. Since the latter lack catalytic activity, two different mechanisms are ...
Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo
(PLoS One 9(10):e109846, 2014-10-07)
Two subtypes of phospholipases A2 (PLA2s) with the ability to induce myonecrosis, ‘Asp49’ and ‘Lys49’ myotoxins, often coexist in viperid snake venoms. Since the latter lack catalytic activity, two different mechanisms are ...
Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site
(Academic Press Inc. Elsevier B.V., 2009-08-01)
Phospholipases A(2) (PLA(2)s) are membrane-associated enzymes that hydrolyze phospholipids at the sn-2 position, releasing lysophospholipids and free fatty acids. Phospholipase A(2) homologues (Lys49-PLA(2)s) are highly ...
Comparative structural studies on Lys49-phospholipases A(2) from Bothrops genus reveal their myotoxic site
(Academic Press Inc. Elsevier B.V., 2009-08-01)
Phospholipases A(2) (PLA(2)s) are membrane-associated enzymes that hydrolyze phospholipids at the sn-2 position, releasing lysophospholipids and free fatty acids. Phospholipase A(2) homologues (Lys49-PLA(2)s) are highly ...
Structure-activity relationship of mastoparan analogs: effects of the number and positioning of Lys residues on secondary structure, interaction with membrane-mimetic systems and biological activity
(Elsevier B. V., 2015-05-02)
In this study, a series of mastoparan analogs were engineered based on the strategies of Ala and Lys scanning in relation to the sequences of classical mastoparans. Ten analog mastoparans, presenting from zero to six Lys ...
Turnover tecidual, desempenho e rendimento de carcaça em frangos de corte submetidos a diferentes níveis de lisina digestível
(Universidade Estadual Paulista (UNESP), 2016)