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CD8(+) T cell adjuvant effects of Salmonella FliCd flagellin in live vaccine vectors or as purified protein
(ELSEVIER SCI LTD, 2010)
Salmonella flagellin, the flagellum structural subunit, has received particular interest as a vaccine adjuvant conferring enhanced immunogenity to soluble proteins or peptides, both for activation of antibody and cellular ...
Head-to-Head Comparison of Three Vaccination Strategies Based on DNA and Raw Insect-Derived Recombinant Proteins against Leishmania
(PUBLIC LIBRARY SCIENCESAN FRANCISCO, 2012)
Parasitic diseases plague billions of people among the poorest, killing millions annually, and causing additional millions of disability-adjusted life years lost. Leishmaniases affect more than 12 million people, with over ...
Evaluation of the immune response to Anaplasma marginale MSP5 protein using a HSV-1 amplicon vector system or recombinant protein
(Elsevier, 2014-11)
Anaplasma marginale is an intraerythrocytic vector-borne infectious agent of cattle. Immunization with the current vaccine, based on parasitized erythrocytes with live Anaplasmacentrale, shows some constraints and confers ...
Evaluation of the immune response to Anaplasma marginale MSP5 protein using a HSV-1 amplicon vector system or recombinant protein
(2014-12)
Anaplasma marginale is an intraerythrocytic vector-borne infectious agent of cattle. Immunization with the current vaccine, based on parasitized erythrocytes with live Anaplasma centrale, shows some constraints and confers ...
Functional analysis of the Brassica napus L. Phytoene Synthase (PSY) gene family
(Public Library of Science, 2014)
Phytoene synthase (PSY) has been shown to catalyze the first committed and rate-limiting step of carotenogenesis in several crop species, including Brassica napus L. Due to its pivotal role, PSY has been a prime target for ...
Avaliação da imunogenicidade de vacinas de DNA e de proteínas recombinantes do envelope dos vírus chikungunya e zika
(Universidade Federal de São Paulo (UNIFESP), 2018-05-24)
Chikungunya (CHIKV) and Zika (ZIKV) viruses’ infection have rapidly enhanced
worldwide in the last decades. To date, there is no vaccine available or specific
treatment against both viruses. The viral envelope proteins ...
Immunisation of cattle against Babesia bovis combining a multi-epitope modified vaccinia Ankara virus and a recombinant protein induce strong Th1 cell responses but fails to trigger neutralising antibodies required for protection
(Elsevier, 2019-10)
Protection against the intraerythrocytic protozoan parasite Babesia bovis depends on both strong innate and adaptive immune response, this latter involving the presentation of parasite antigens to CD4+ T-lymphocytes by ...
Waning and boosting of antibody Fc-effector functions upon SARS-CoV-2 vaccination
(SPRINGER INTERNATIONAL PUBLISHING AG, 2023)
Efficiency of SARS-CoV-2 vaccines has long been attributed to the neutralising capacity of the antibodies that are produced upon prime-boost vaccinations. Here authors show that upon vaccination with CoronaVac and BNT162b2 ...