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N-Glycosylation in piroplasmids: diversity within simplicity
(Multidisciplinary Digital Publishing Institute, 2021-01)
N-glycosylation has remained mostly unexplored in Piroplasmida, an order of tick-transmitted pathogens of veterinary and medical relevance. Analysis of 11 piroplasmid genomes revealed three distinct scenarios regarding ...
Evidence for glycosylation on a DNA-binding protein of Salmonella enterica
(2007-04-02)
Abstract
Background
All organisms living under aerobic atmosphere have powerful mechanisms that confer their macromolecules protection against oxygen reactive species. ...
Evidence for glycosylation on a DNA-binding protein of Salmonella enterica
(2007-04-02)
Abstract
Background
All organisms living under aerobic atmosphere have powerful mechanisms that confer their macromolecules protection against oxygen reactive species. ...
Rhodococcus erythropolis as a host for expression, secretion and glycosylation of Mycobacterium tuberculosis proteins
(BIOMED CENTRAL LTD., 2017-01-19)
Background: Glycosylation is one of the most abundant posttranslational polypeptide chain modification in nature. Although carbohydrate modification of protein antigens from many microbial pathogens constitutes important ...
Oligosaccharide residues of Loxosceles intermedia (brown spider) venom proteins: dependence on glycosylation for dermonecrotic activity
(Elsevier B.V., 1999-04-01)
Loxosceles spp. (brown spider) envenomation has been reported to provoke dermonecrosis and haemorrhage at the bite site (a hallmark of accidents) and, to a lesser extent, thrombocytopenia, hemolysis and disseminated ...
Bifunctional GM-CSF-derived peptides as tools for O-glycoengineering and protein tagging
(Elsevier Science, 2021-02)
Rapid development of effective biotherapeutics has been a concern during the last couple decades. In our work we designed two novel peptide tags, GMOP and mGMOP, derived from the N-terminal region of human granulocyte and ...
Thermodynamic and structural aspects of molecular recognition in mannose-binding protein complexes: a theoretical study over HRP-ArtinM association
(Springer, 2021-03-15)
The biomolecular recognition of D-mannose-binding lectin from Artocarpus heterophyllus (ArtinM) by Horseradish Peroxidase (HRP) mediated by glycosylation allows their application in a multitude of biological systems. The ...
Glycosylation of glycolipids in cancer: basis for development of novel therapeutic approaches
(Frontiers, 2013-12)
Altered networks of gene regulation underlie many pathologies, including cancer. There are several proteins in cancer cells that are turned either on or off, which dramatically alters the metabolism and the overall activity ...