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Mostrando ítems 71-80 de 97
Child Abuse, Depression, and Methylation in Genes Involved With Stress, Neural Plasticity, and Brain Circuitry
(Elsevier B.V., 2014-04-01)
Objectives: To determine whether epigenetic markers predict dimensional ratings of depression in maltreated children. Method: A genome-wide methylation study was completed using the Iliumina 450K BeadChip array in 94 ...
Cardiomiócitos humanos derivados de células tronco pluripotentes induzidas: aspectos morfológicos e funcionais
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2017-09-15)
The advent of induced pluripotent human stem cells (hiPSC or iPSCs) has caused great expectations in the scientific and clinical field. Since they are derived from somatic cells, they can grow indefinitely in vitro without ...
LPS regulates the expression of glucocorticoid receptor alpha and beta isoforms and induces a selective glucocorticoid resistance in vitro
(Biomed Central Ltd., 2017)
Background: This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in ...
RSUME enhances Glucocorticoid Receptor SUMOylation and transcriptional activity
(American Society for Microbiology, 2013-06)
Glucocorticoid receptor (GR) activity is modulated by posttranslational modifications, including phosphorylation, ubiquitination, and SUMOylation. The GR has three SUMOylation sites: lysine 297 (K297) and K313 in the ...
Evaluación de un modelo de interacción gen-ambiente en pacientes con trastorno bipolar tipo I en eutimia : asociación entre maltrato infantil y cognición social, y moderación de polimorfismos genéticos
(2020)
La presente tesis estudió la evaluación de un modelo de interacción gen-ambiente en pacientes con Trastorno Bipolar (TB) tipo I en eutimia , midiendo la asociación entre el antecedente de maltrato infantil y el funcionamiento ...
Effect of exercise training on Ca2+ release units of left ventricular myocytes of spontaneously hypertensive rats
(Brazilian Journal of Medical and Biological Research, 2017)
Association of an IRF3 putative functional uORF variant with resistance to Brucella infection: A candidate gene based analysis of InDel polymorphisms in goats
(Academic Press Ltd - Elsevier Science Ltd, 2019-03)
Brucellosis is an important zoonotic disease caused by infection with Brucella spp. It generates major economic losses in livestock production worldwide. Goats are the principal hosts of B. melitensis, the main infection ...
Association of an IRF3 putative functional uORF variant with resistance to Brucella infection: A candidate gene based analysis of InDel polymorphisms in goats
(Elsevier, 2019-03)
Brucellosis is an important zoonotic disease caused by infection with Brucella spp. It generates major economic losses in livestock production worldwide. Goats are the principal hosts of B. melitensis, the main infection ...