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The role of the α cell in the pathogenesis of diabetes : A world beyond the mirror
(2021-09-01)
Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic metabolic disorders, and insulin has been placed at the epicentre of its pathophysiological basis. However, the involvement of impaired alpha (α) cell ...
Viral, host and environmental factors that favor anthropozoonotic spillover of coronaviruses: An opinionated review, focusing on SARS-CoV, MERS-CoV and SARS-CoV-2
Environmental factors play a key role in the zoonotic transmission of emerging
pathogenic viruses as mankind is constantly disturbing wildlife’s ecosystems usually by
cutting down forests to build human settlements or ...
Inhibidores de dipeptidil dipeptidasa-IV: de la teoría a la práctica
(Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina, 2015-04-01)
Esta revisión de los inhibidores de dipeptidil peptidasa-IV busca motivar el uso racional de tal grupo farmacológico en la práctica diaria. Este grupo es una nueva opción terapéutica en monoterapia o terapia combinada para ...
Albumin from erythrina edulis (Pajuro) as a promising source of multifunctional peptides
(MDPI, 2021)
Multifunctional peptides, capable of acting on different body systems through multiple
mechanisms of action, offer many advantages over monofunctional peptides, including lower adverse
side effects and costs. Erythrina ...
Genome-Wide Association for Growth Traits in Canchim Beef Cattle
(Public Library Science, 2014-04-14)
Studies are being conducted on the applicability of genomic data to improve the accuracy of the selection process in livestock, and genome-wide association studies (GWAS) provide valuable information to enhance the ...
Using Computer-aided Drug Design and Medicinal Chemistry Strategies in the Fight Against Diabetes
(ADENINE PRESS, 2011)
The aim of this work is to present a simple, practical and efficient protocol for drug design, in particular Diabetes, which includes selection of the illness, good choice of a target as well as a bioactive ligand and then ...
Efeitos da sitagliptina no tecido ósseo em ratos diabéticos e não diabéticos
(Universidade Estadual Paulista (Unesp), 2018-05-30)
A diabetes mellitus, doença caracterizada pelo aumento da glicemia no sangue, é um dos mais importantes problemas de saúde pública do mundo, com incidência crescente, sobretudo em países em desenvolvimento. Novas terapias ...
Impaired Incretin Secretion And Pancreatic Dysfunction With Older Age And Diabetes
(W.B. Saunders, 2014)
Biologic and physiologic actions of GLP-1Acciones biológicas y fisiológicas del GLP-1
(Universidad de Costa Rica, 2019)