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Theory of inpatient circadian care (TICC): A proposal for a middle-range theory
(Bentham Science Publishers B.V., 2015-01)
The circadian system controls the daily rhythms of a variety of physiological processes. Most organisms show physiological, metabolic and behavioral rhythms that are coupled to environmental signals. In humans, the main ...
Zebrafish arylalkylamine-N-acetyltransferase genes: targets for regulation of the circadian clock
(BioScientifica, 2006-04)
Daily rhythms of melatonin production are controlled by changes in the activity of arylalkylamine-N-acetyltransferase (AANAT). Zebrafish possess two aanats, aanat1 and aanat2; the former is expressed only in the retina and ...
Circadian clock regulation of the glycogen synthase (gsn) gene by WCC is critical for rhythmic glycogen metabolism in Neurospora crassa
(Natl Acad Sciences, 2019-05-21)
Circadian clocks generate rhythms in cellular functions, including metabolism, to align biological processes with the 24-hour environment. Disruption of this alignment by shift work alters glucose homeostasis. Glucose ...
Elovl3: a model gene to dissect homeostatic links between the circadian clock and nutrition status
(American Society for Biochemistry and Molecular Biology, 2006-12)
The ELOVL3 protein is a very long-chain fatty acid elongase found in liver, skin, and brown adipose tissues. Circadian expression of the Elovl3 gene in the liver is perturbed in mutant CLOCK mice but persists in mice with ...
Effect of an intracerebroventricular injection of aggregated Beta-amyloid (1–42) on daily rhythms of oxidative stress parameters in the prefrontal cortex
(Elsevier, 2021-03-15)
Accumulation of amyloid peptides in the brain plays a key role in the pathogenesis of Alzheimer's disease (AD). Aggregated beta-amyloid (Aβ) peptide increases intracellular reactive oxygen species associated to a deficient ...
Daily patterns of activity in free-living Rio Negro Tuco-Tucos (Ctenomys rionegrensis)
(Sociedad Argentina para el Estudio de los Mamíferos, 2016)
Activity patterns are a fundamental aspect of the biology of many species, with important implications
for survival and reproduction. Typically, such patterns of activity are thought to be entrained by light cues,
raising ...
Deciphering the function of the blunt circadian rhythm of melatonin in the newborn lamb: impact on adrenal and heart
(Oxford University Press, 2017)
Neonatal lambs, as with human and other neonates, have low arrhythmic endogenous levels of melatonin for several weeks until they start their own pineal rhythm of melatonin production at approximately 2 weeks of life. ...
Circadian variation in Pseudomonas fluorescens (CHA0)-mediated paralysis of Caenorhabditis elegans
(Academic Press Ltd - Elsevier Science Ltd, 2011-01)
Abiotic and biotic environmental stressors play a key role in the ecophysiology of most organisms. As the presence and activity of stress-inducing agents vary along the day, organisms that are able to predict these periodic ...