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Susceptibility to Yersinia pseudotuberculosis Infection is Linked to the Pattern of Macrophage Activation
(Wiley-Blackwell Publishing, Inc, 2009-04-01)
T helper 1 cells play a crucial role in the clearance of Yersinia pseudotuberculosis infection. By producing cytokines and presenting antigens to T cells, activated macrophages can orientate the adaptive immune response. ...
Role for Tetrahydrobiopterin in the Fetoplacental Endothelial Dysfunction in Maternal Supraphysiological Hypercholesterolemia
(Hindawi, 2016)
Maternal physiological hypercholesterolemia occurs during pregnancy, ensuring normal fetal development. In some cases,
the maternal plasma cholesterol level increases to above this physiological range, leading to maternal ...
Susceptibility to Yersinia pseudotuberculosis Infection is Linked to the Pattern of Macrophage Activation
(Wiley-Blackwell Publishing, Inc, 2009-04-01)
T helper 1 cells play a crucial role in the clearance of Yersinia pseudotuberculosis infection. By producing cytokines and presenting antigens to T cells, activated macrophages can orientate the adaptive immune response. ...
Role for tetrahydrobiopterin in the fetoplacental endothelial dysfunction in maternal supraphysiological hypercholesterolemia
(2016)
Maternal physiological hypercholesterolemia occurs during pregnancy, ensuring normal fetal development. In some cases, the maternal plasma cholesterol level increases to above this physiological range, leading to maternal ...
Pathogenic Mycobacterium bovis strains differ in their ability to modulate the proinflammatory activation phenotype of macrophages
(2012-08-03)
Abstract
Background
Tuberculosis, caused by Mycobacterium tuberculosis or Mycobacterium bovis, remains one of the leading infectious diseases worldwide. The ability of ...
Pathogenic Mycobacterium bovis strains differ in their ability to modulate the proinflammatory activation phenotype of macrophages
(2012-08-03)
Abstract
Background
Tuberculosis, caused by Mycobacterium tuberculosis or Mycobacterium bovis, remains one of the leading infectious diseases worldwide. The ability of ...
Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1 alpha S-Nitrosylation and Transcriptional Activity in Hypoxia
(MDPI, 2020)
Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently hypoxic and the ...
Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia
(2020)
Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently hypoxic and the ...
TNFR1, o maestro do processo inflamatório na infeção por Leishmania amazonensis
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2021-07-09)
TNF is pleiotropic cytokine involved in inflammation, host defense, tissue degeneration, tissue regeneration among other functions. TNF acts through two cognate receptors. TNFR1 seems to be more effective against intracellular ...
Caveolin-1-mediated tumor suppression is linked to reduced hif1α s-nitrosylation and transcriptional activity in hypoxia
(2020-09)
Caveolin-1 (CAV1) is a well-established nitric oxide synthase inhibitor, whose function as a tumor suppressor is favored by, but not entirely dependent on, the presence of E-cadherin. Tumors are frequently hypoxic and the ...