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Functionality of the Interleukin 8 haplotypes in lymphocytes and macrophages in response to gram-negative periodontopathogens
(2019-03-20)
Individuals carrying the ATC/TTC haplotype (Hap-1) in the interleukin 8 (IL8) gene were reported as more susceptible to chronic periodontitis (CP), an infectious disease associated with Gram-negative bacteria, in comparison ...
Effect of doxorubicin on cytokine production by lymphocytes and the Th1/Th2 balance
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2010)
Doxorubicin (DOXO) is a potent chemotherapeutic used mainly against solid tumours; however, it has several side effects that can limit its clinical use. On the other hand, the effect of DOXO upon lymphocyte function is ...
Alterations of cell-mediated immune response in children with febrile seizures
(1997-06-01)
The aim of the present investigation was to study the distribution of T-cell subsets in peripheral blood defined by monoclonal antibodies and by the lymphocyte proliferative response to phytohemagglutinin (PHA) in 30 ...
Alterations of cell-mediated immune response in children with febrile seizures
(1997-06-01)
The aim of the present investigation was to study the distribution of T-cell subsets in peripheral blood defined by monoclonal antibodies and by the lymphocyte proliferative response to phytohemagglutinin (PHA) in 30 ...
Inhibitory Signals Mediated by Programmed Death-1 Are Involved With T-Cell Function in Chronic Periodontitis
(AMER ACAD PERIODONTOLOGY, 2009)
Background: Inhibitory signals mediated via molecules such as programmed death-1 (PD-1) play a critical role in downmodulating immune responses and maintaining peripheral tolerance. We investigated the involvement of ...
Lepromatous leprosy: Study of some subpopulations of lymphocytes and its functional analysis
(1985)
Total T lymphocyte levels were investigated in a group of patients with lepromatous leprosy and in clinically healthy individuals, by the capacity to form E rosettes, together with Fc-gamma suppressor T lymphocytes and ...
Lepromatous leprosy: Study of some subpopulations of lymphocytes and its functional analysis
(1985)
Total T lymphocyte levels were investigated in a group of patients with lepromatous leprosy and in clinically healthy individuals, by the capacity to form E rosettes, together with Fc-gamma suppressor T lymphocytes and ...
CXCL12 is a costimulator for CD4+ T cell activation and proliferation in chronic lymphocytic leukemia patients
(Springer, 2013-01)
Activated T cells from patients with chronic lymphocytic leukemia (CLL) provide survival and proliferative signals to the leukemic clone within lymphoid tissues. Recruitment of both, CLL cells and T lymphocytes, to this ...
γδ T lymphocytes: An effector cell in autoimmunity and infection
(Frontiers Media SA, 2018-10)
γδ T cells are non-conventional lymphocytes which show several properties of innate immune cells. They present a limited TCR repertoire and circulate as cells with a pre-activated phenotype thus being able to generate rapid ...
Characterizing the role of mitochondrial Ca2+ overload and permeability transition during the BCR-dependent activation of murine B lymphocytes
(2017-12-05)
Mitochondria have proved their role as major players for immunometabolism, regulating cell function by metabolic signals. Indeed, mitochondrial function during lymphocyte activation goes beyond ATP supply, as recent evidence ...