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Synergism between dexketoprofen and meloxicam in an orofacial formalin test was not modified by opioid antagonists
(Elsevier B.V., 2011)
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs for the management of acute and chronic pain. The role of the opioid system in the synergism between NSAIDs is not well characterized. ...
Concurrent nociceptive stimulation impairs the anxiolytic effect of midazolam injected into the periaqueductal gray in mice
(Elsevier B.V., 2005-06-14)
This study investigated whether the opportunity to avoid or escape the open arms of an elevated plus-maze (EPM) affects the antinociceptive response observed when mice are subjected to open arm confinement. Furthermore, ...
Concurrent nociceptive stimulation impairs the anxiolytic effect of midazolam injected into the periaqueductal gray in mice
(Elsevier B.V., 2005-06-14)
This study investigated whether the opportunity to avoid or escape the open arms of an elevated plus-maze (EPM) affects the antinociceptive response observed when mice are subjected to open arm confinement. Furthermore, ...
PERIPHERAL ESTRADIOL INDUCES TEMPOROMANDIBULAR JOINT ANTINOCICEPTION IN RATS BY ACTIVATING THE NITRIC OXIDE/CYCLIC GUANOSINE MONOPHOSPHATE SIGNALING PATHWAY
(Pergamon-elsevier Science LtdOxfordInglaterra, 2009)
Corticosterone does not change open elevated plus maze-induced antinociception in mice
(Academic Press Inc. Elsevier B.V., 2014)
Alterations in PTEN, MDM2, TP53 and AR protein and gene expression are associated with canine prostate carcinogenesis
(2016-06-01)
The PTEN, AR, MDM2 and p53 protein network plays a central role in the development of many human cancers, thus eliciting the development of targeted cancer therapeutics. Dogs spontaneously develop tumours, and they are ...
Participación de los receptores 5-HT3 en el desarrollo y mantenimiento de la hiperalgesia y alodinia secundarias inducidas con formalina
(2011-07-25)
The 5-HT3 receptor belongs to the super family of ligand gated ion channels, consists of five subunits that are assembled so as to form a central ion channel. In human 5 subunits have been cloned (5-HT3A/B/C/D/E/Ea) however, ...