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Effect of salivary CYP4EM1 and CYP4EM2 gene silencing on the life span of Chagas disease vector Rhodnius prolixus (Hemiptera, Reduviidae) exposed to sublethal dose of deltamethrin
(Blackwell Scientific For The Royal Entomological Society, 2023)
Genomic regions harboring insecticide resistance-associated Cyp genes are enriched by transposable element fragments carrying putative transcription factor binding sites in two sibling Drosophila species
(Elsevier B.V., 2014-03-01)
In the present study, an in silico analysis was performed to identify transposable element (TE) fragments inserted in Cyps with functions associated with resistance to insecticides and developmental regulation as well as ...
Microarray analysis of cytochrome P450 mediated insecticide resistance in Drosophila
(Elsevier B.V., 2014)
Expressão dos genes CYP1A1, CYP1B1, CYP2A6 e CYP2E1 em fumantes com câncer bucal.
(Universidade Estadual Paulista (Unesp), 2018-02-05)
Os carcinógenos do tabaco estão relacionados a diversos tipos de câncer incluindo o carcinoma de células escamosas (CCE) bucal. Aliado ao álcool, o tabaco contribui para o desfecho desfavorável destes casos. A susceptibilidade ...
In vitro inhibition of human CYP2D6 by the chiral pesticide fipronil and its metabolite fipronil sulfone: Prediction of pesticide-drug interactions
(2019-10-01)
Fipronil is a chiral insecticide employed worldwide in crops, control of public hygiene and control of veterinary pests. Humans can be exposed to fipronil through occupational, food, and environmental contamination. ...
Effects of aflatoxin B1, fumonisin B1 and their mixture on the aryl hydrocarbon receptor and cytochrome P450 1A induction
(Pergamon-Elsevier Science Ltd, 2015-01)
Aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are mycotoxins widely found as cereal contaminants and their co-occurrence in corn has been associated with a high incidence of liver cancer. Both toxins are immunotoxic, with ...
Melatonin protects the cytochrome P450 system through a novel antioxidant mechanism
(ELSEVIER IRELAND LTD, 2010)
Melatonin, an endogenous hormone, is used as an antioxidant drug in doses quite higher than the endogenous circulating levels of this hormone. Hepatic endoplasmic reticulum contains the cytochrome P450 (CYP450) system, ...
Identification of three cytochrome P450 genes in the Chagas' disease vector Triatoma infestans : Expression analysis in deltamethrin susceptible and resistant populations
(Elsevier Science, 2016-05)
Cytochrome P450 monooxygenases play a predominant role in the metabolism of insecticides. Many insect P450genes have frequently been associated with detoxification processes allowing the insect to become tolerant orresistant ...