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On the spacetime connecting two aeons in conformal cyclic cosmology
(Springer, 2015-12-01)
As quotient spaces, Minkowski and de Sitter are fundamental, non-gravitational spacetimes for the construction of physical theories. When general relativity is constructed on a de Sitter spacetime, the usual Riemannian ...
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine
(2005-10-01)
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of nucleosides and deoxynucleosides, generating ribose 1-phosphate and the purine base, which is an important step of purine catabolism pathway. ...
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine
(2005-10-01)
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of nucleosides and deoxynucleosides, generating ribose 1-phosphate and the purine base, which is an important step of purine catabolism pathway. ...
Solvent effects in the conformational stability of alpha-substituted acetamides through theoretical and experimental data
(Elsevier Science BvAmsterdamHolanda, 2008)
Evolutionary Conserved Positions Define Protein Conformational Diversity
(Public Library of Science, 2016-03)
Conformational diversity of the native state plays a central role in modulating protein function. The selection paradigm sustains that different ligands shift the conformational equilibrium through their binding to ...
The Intriguing Phospholipases A(2) Homologues: Relevant Structural Features on Myotoxicity and Catalytic Inactivity
(Bentham Science Publ Ltd, 2009-08-01)
Phospholipases A(2) homologues are found in the venom of Crotalinae snakes, being their main action related to myonecrosis induction. Although many studies on these toxins had already been performed, their mechanism of ...
The Intriguing Phospholipases A(2) Homologues: Relevant Structural Features on Myotoxicity and Catalytic Inactivity
(Bentham Science Publ Ltd, 2009-08-01)
Phospholipases A(2) homologues are found in the venom of Crotalinae snakes, being their main action related to myonecrosis induction. Although many studies on these toxins had already been performed, their mechanism of ...
The intriguing phospholipases A2 homologues: Relevant structural features on myotoxicity and catalytic inactivity
(2009-08-01)
Phospholipases A2 homologues are found in the venom of Crotalinae snakes, being their main action related to myonecrosis induction. Although many studies on these toxins had already been performed, their mechanism of action ...