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Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system
(Public Library of Science, 2020-05)
T cell epitope candidates are commonly identified using computational prediction tools in order to enable applications such as vaccine design, cancer neoantigen identification, development of diagnostics and removal of ...
Caracterização da resposta imune induzida pelo vírus Vaccinia Ankara modificado (MVA) em modelo murino
(Universidade Federal de Minas GeraisUFMG, 2011-03-01)
Since 1796, when the British physician Edward Jenner introduced the concept of vaccination, it became the most important intervention strategy developed to prevent the onset of infectious diseases. Nevertheless, none of ...
Avaliação sorológica de rebanhos bubalinos para vírus causadores de doenças reprodutivas e vesiculares
(Universidade Federal de Santa MariaBrasilUFSMCentro de Ciências Rurais, 2021-02-23)
Buffaloes are rustic animals with high adaptability in different climates and regions. Buffaloes are an alternative for meat and milk production in the livestock sector, besides having greater resistance to diseases. ...
Atividade virucida de porfirinas tetra-platinadas frente a vírus de bovinos
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2018-02-26)
Porphyrins are photosensitizing (PS) substances, that is, compounds that are activated
when exposed to light, reacting with oxygen molecules and producing reactive oxygen
species (ROS). The porphyrins are composed of ...
Aspectos clínico-patológicos das poxviroses em bovinos no Distrito Federal (2015-2018)
(2019-07-10)
Foi realizado estudo retrospectivo de casos de poxviroses diagnosticadas e notificadas em bovinos, no Distrito Federal (DF), entre 2015 a 2018, pelo Serviço Oficial Veterinário da Secretaria de Agricultura, Abastecimento ...
Indução do estresse do retículo endoplasmático celular pelo Vaccinia virus: modulação da via UPR durante a infecção viral
(Universidade Federal de Minas GeraisUFMG, 2013-10-30)
The unfolded protein response (UPR) is a cellular response to accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER), induced by a variety of external and internal stimuli, including accumulation ...
Linfócitos T CD4+ e CD8+ participam da resposta imune de memória contra a infecção humana natural pelo vaccinia virus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2013-12-18)
The present study evaluates the immune response of memory CD4+ and CD8+ T cells from patients following a natural Vaccinia virus (VACV) infection. A total of 42 individuals were involved in the study being: 22 previously ...