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The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-beta-dependent Signaling, and Inhibits TGF-beta-dependent Fibrotic Response in Skeletal Muscles
(American Society for Biochemistry and Molecular Biology, 2012)
Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and ...
TGF-β and new bone formation
(2006-09-01)
The aim of this work is to present, by a literature review, the principal characteristics of TGF-beta, in the regulation and new bone formation. © 2007 Sociedad Chilena de Anatomía.
Role of TGF-β1 in the behavior disorders
(IOS Press, 2015-11)
Transforming growth factor 1 (TGF-β1) is an anti-inflammatory cytokine that is expressed in different regions of the mammalian brain, and at all developmental ages. This cytokine can modulate neuron differentiation and ...
FoxO1 mediates TGF-beta1-dependent cardiac myofibroblast differentiation
(Elsevier, 2016)
© 2015 Elsevier B.V. Cardiac fibroblast differentiation to myofibroblast is a crucial process in the development of cardiac fibrosis and is tightly dependent on transforming growth factor beta-1 (TGF-β1). The transcription ...
TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease
(Public Library of Science, 2020)
Associação de polimorfismos no gene do TGF-β1 com asma, marcadores de alergia e infecções helmínticas
(Instituto de Ciências da Saúdeem ImunologiaUFBAbrasil, 2015-02-23)
A prevalência das doenças alérgicas vem crescendo em ritmo acelerado em todo o
mundo estando inversamente associado à redução dos níveis de infecções. Estudos
sugerem que no caso de infecções por helmintos existe a ...
TGF-β and new bone formation
(2014)
The TGF-β co-receptor endoglin modulates the expression and transforming potential of H-Ras
(Oxford University Press, 2010)
Endoglin is a coreceptor for transforming growth factor-β (TGF-β) that acts as a suppressor of malignancy during mouse skin carcinogenesis. Because in this model system H-Ras activation drives tumor initiation and progression, ...