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Mostrando ítems 61-69 de 106
Neogenina 1 actúa como un blanco transcripcional directo de la vía Sonic Hedgehog/Gli en línea celular de neuroblastoma humano
(Universidad de Chile, 2012)
El desarrollo embrionario en vertebrados es coordinado por una red de señales y factores de crecimiento que comandan diferentes procesos celulares. Sonic Hedgehog (SHH), es un ligando considerado como un regulador maestro ...
Evaluación de neogenina-1 como gen blanco de la vía sonic hedgehog en carcinoma basocelular
(Universidad de Chile, 2015)
El Carcinoma Basocelular Cutáneo (BCC), un tipo de cáncer de piel, es una de las neoplasias más frecuentes en el ser humano. Es causado por una desregulación de la vía Sonic Hedgehog/Gli (Shh/Gli), cuya señalización juega ...
Changes in synaptic transmission and protein expression in the brains of adult offspring after prenatal inhibition of the kynurenine pathway
(Elsevier, 2013-10)
During early brain development, N-methyl-D-aspartate (NMDA) receptors are involved in cell migration, neuritogenesis, axon guidance and synapse formation, but the mechanisms which regulate NMDA receptor density and function ...
Eventos epigenéticos no ameloblastoma: um enfoque na metilação e transcrição de metaloproteinases da matriz e perda de heterozigosidade do gene PTCH
(Universidade Federal de Minas GeraisUFMG, 2012-05-25)
Ameloblastoma is a benign odontogenic neoplasm with an aggressive behavior and high recurrence rates. Some studies have been performed to elucidated molecular mechanisms and genetic alterations evolving tumor pathogenesis. ...
Shh signaling through the primary cilium modulates rat oligodendrocyte differentiation
(2015)
Primary Cilia (PC) are a very likely place for signal integration where multiple signaling pathways converge. Two major signaling pathways clearly shown to signal through the PC, Sonic Hedgehog (Shh) and PDGF-Ra, are ...
Shh Signaling through the Primary Cilium Modulates Rat Oligodendrocyte Differentiation.
(2015)
Primary Cilia (PC) are a very likely place for signal integration where multiple signaling pathways converge. Two major signaling pathways clearly shown to signal through the PC, Sonic Hedgehog (Shh) and PDGF-Rα, are ...
Shh Signaling through the Primary Cilium Modulates Rat Oligodendrocyte Differentiation.
(2015)
Primary Cilia (PC) are a very likely place for signal integration where multiple signaling pathways converge. Two major signaling pathways clearly shown to signal through the PC, Sonic Hedgehog (Shh) and PDGF-Rα, are ...