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In vivo effects of TGF beta 1 on the the growth of gastric epithelium in suckling rats
(ELSEVIER SCIENCE BV, 2008)
As the content of Transforming Growth Factor-beta (TGF beta) wanes in the milk of lactating rat, an increase in TGF beta is observed in the gastric epithelia concomitant with differentiation of the glands upon weaning. ...
Extracellular matrix remodeling and TGF-β1/Smad signaling in diabetic colon mucosa
(Academic Press Ltd - Elsevier Science Ltd, 2017-12)
Diabetes is associated with metabolic and functional alterations in the gut. Using an experimental model of streptozotocin (STZ)-induced diabetes in rodents, we analyzed the extracellular matrix (ECM) and TGF-β/Smad signaling ...
Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney
(Springer, 2017-06)
Uric acid (UA) has been associated with renal fibrosis and progression of chronic kidney disease. However, the underlying mechanisms of this process have still not been identified. Here, we studied the role of the innate ...
Papel de la proteína QM en las vías de transducción de señales y la progresión tumoral inducidas por TGF-[beta]1 en células transformadas
(Universidad de ChilePrograma Cybertesis, 2007)
TGF-β1 es uso de los miembros de la superfamilia de TGF-β, capaz de activar vías de señalización dentro de la célula que modulan la expresión de diversos genes. Entre estas vías encontramos a los complejos Smad2, Smad3 y ...
Involvement of MEK/ERK1/2 and PI3K/Akt pathways in the refractory behavior of GH3B6 Pituitary tumor cells to the inhibitory effect of TGFß1
(Endocrine Society, 2015-02)
Pituitary tumor cells have a poor response to the growth inhibitory effect of TGFβ1, possibly resulting from the cross talk of TGFβ/Smads signal with other signaling pathways, an undescribed mechanism in these tumoral ...
Caracterización del Inmunofenotipo para el EGFR, TBXA2R Y SMAD3 En Arreglos de Tejido para el Diagnóstico Diferencial Entre Adenoma e Hiperplasia Paratiroidea en una Muestra de Pacientes Intervenidos Quirúrgicamente por HPTP no Familiar
(2011-12-17)
Backround: Primary hyperparathyroidism (pHPT) is a relatively common endocrinophathy. Its
real incidence resides among women and people older than 60 years of age. It occurs as a
consequence of an excessive secretion of ...