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Mostrando ítems 61-70 de 97
Activated α2-macroglobulin induces Müller glial cell migration by regulating MT1-MMP activity through LRP1
(Federation of American Societies for Experimental Biology, 2013-05)
In retinal proliferative diseases, Müller glial cells (MGCs) acquire migratory abilities. However, the mechanisms that regulate this migration remain poorly understood. In addition, proliferative disorders associated with ...
Membrane cycling after the excess retrieval mode of rapid endocytosis in mouse chromaffin cells
(Wiley, 2013-03)
Aim: After exocytosis, neuroendocrine cells and neurones keep constant the plasma membrane and the releasable vesicle pools by performing endocytosis and vesicular cycling. Patch-clamp capacitance measurements on chromaffin ...
Mas receptor is translocated to the nucleus upon agonist stimulation in brainstem neurons from spontaneously hypertensive rats but not normotensive rats
(Oxford University Press, 2020-06)
Aims: Activation of the angiotensin (Ang)-(1-7)/Mas receptor (R) axis protects from sympathetic overactivity. Endocytic trafficking is an essential process that regulates receptor (R) function and its ultimate cellular ...
Glutamatergic Receptor Trafficking and Delivery: Role of the Exocyst Complex
(NLM (Medline), 2020)
Cells comprise several intracellular membrane compartments that allow them to function properly. One of these functions is cargo movement, typically proteins and membranes within cells. These cargoes ride microtubules ...
Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE
(2022-12-07)
Hedgehog proteins (Hhs) secretion from apical and/or basolateral domains occurs in different epithelial cells impacting development and tissue homeostasis. Palmitoylation and cholesteroylation attach Hhs to membranes, and ...
Endocytic Rabs Are Recruited to the Trypanosoma cruzi Parasitophorous Vacuole and Contribute to the Process of Infection in Non-professional Phagocytic Cells
(Frontiers Media S.A., 2020-10)
Trypanosoma cruzi is the parasite causative of Chagas disease, a highly disseminated illness endemic in Latin-American countries. T. cruzi has a complex life cycle that involves mammalian hosts and insect vectors both of ...
Phosphatidic Acid Induces Ligand-independent Epidermal Growth Factor Receptor Endocytic Traffic through PDE4 Activation
(AMER SOC CELL BIOLOGY, 2010)
Endocytosis modulates EGFR function by compartmentalizing and attenuating or enhancing its ligand-induced signaling. Here we show that it can also control the cell surface versus intracellular distribution of empty/inactive ...
Phosphatidic acid induces ligand-independent epidermal growth factor receptor endocytic traffic through PDE4 activation
(2010-08-15)
Endocytosis modulates EGFR function by compartmentalizing and attenuating or enhancing its ligand-induced signaling. Here we show that it can also control the cell surface versus intracellular distribution of empty/inactive ...
Relación entre la estructura y la función de M6a: endocitosis y reciclado
(2019-03-27)
La glicoproteína de membrana M6a se encuentra asociada a enfermedades neuropsiquiátricas como la depresión, la esquizofrenia y fallas en el aprendizaje. Se ha descripto que contribuye positivamente en la extensión de ...