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Microencapsulation of cellular aggregates composed of diferentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue
(2020)
Background: In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transplant ...
Secreção de insulina, sinalização de Ca2+ e função mitocondrial em ilhotas de ratas senescentes
(Universidade Federal de São Paulo (UNIFESP), 2010-08-25)
Aging is associated with changes in pancreatic β cells sensitivity to nutrients resulting in glucose intolerance and diabetes mellitus (DM) type 2 (DM 2) development. Here the study cells function Ca2+ signaling, mitochondrial ...
Islet neogenesis-associated protein (INGAP)-positive cell mass, β-cell mass, and insulin secretion: their relationship during the fetal and neonatal periods
(Lippincott Williams & Wilkins, 2013-04)
Objectives: To study the chronological appearance of pancreatic islet neogenesis–associated protein (INGAP)-positive cells and its correlation with the increase in β-cell mass and function in fetal and neonatal rats.
Methods: ...
Impact of dietary fatty acids on lipid profile, insulin sensitivity and functionality of pancreatic β cells in type 2 diabetic subjects Impacto de los ácidos grasos de la dieta sobre el perfil lipídico, la sensibilidad a la insulina y la funcionalidad de
(Grupo Aula Medica S.A., 2015)
© 2015 Grupo Aula Medica S.A. All rights reserved.Introduction: the quality of fats could influence the metabolic control of patients with Type 2 Diabetes Mellitus (DM2). Objectives: to determine the relationship between ...
Pancreatic islet transplantation
(2009)
Abstract
Background
No formulation of exogenous insulin available to date has yet been able to mimic the physiological nictemeral rhythms of this hormone, and despite all engineering advancements, the theoretical ...