Buscar
Mostrando ítems 61-70 de 395
Enzymatic and chemical synthesis of new anticoagulant peptides
(American Chemical Society, 2018-09)
In this study we report the enzymatic synthesis of N-α-[Carbobenzyloxy]-Tyr-Gln-Gln (Z-YQQ), a new anticoagulant tripeptide. It was obtained using phytoproteases from the stems and petioles of Asclepias curassavica L. as ...
Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains.
(Springer/Plenum Publishers, 2000-12)
Insulin degrading enzyme (IDE) is a metalloprotease that has been involved in amyloid beta peptide (A(beta)) degradation in the brain. We analyzed the ability of human brain soluble fraction to degrade A(beta) analogs 1-40, ...
Labaditin, a cyclic peptide with rich biotechnological potential: preliminary toxicological studies and structural changes in water and lipid membrane environment
(Springer, 2011-01-01)
Cyclic peptides isolated from the plants of the Euphorbiaceae family have been largely studied due to their rigid conformation, which is considered significant for biologic activity. The peptide Labaditin (L(0)) and its ...
BRADYKININ POTENTIATING and SENSITIZING ACTIVITIES of NEW SYNTHETIC ANALOGS of SNAKE-VENOM PEPTIDES
(Amer Chemical Soc, 1977-01-01)
EFFECT of TYROSINE IONIZATION UPON BIOLOGICAL-ACTIVITIES of ANGIOTENSIN-II and 2 NEW PEPTIDE ANALOGS
(Elsevier B.V., 1977-01-01)
Conformational Properties of Angiotensin II and Its Active and Inactive TOAC-Labeled Analogs in the Presence of Micelles. Electron Paramagnetic Resonance, Fluorescence, and Circular Dichroism Studies
(JOHN WILEY & SONS INC, 2009)
The interaction between angiotensin II (AII, DRVYIHPF) and its analogs carrying 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid (TOAC) and detergents-negatively charged sodium dodecyl sulfate (SDS) and ...
Gut microbiota and antimicrobial peptides
(2017-02-01)
This mini-review covers the potential interactions between gut microbiota and antimicrobial peptides, as well as the main mechanisms of action of antimicrobial peptides. One of the most efficient molecules produced by ...
Estudos bioquímicos, farmacológicos e de minimização da estrutura do peptídeo TsHpT-I isolado do veneno do escorpião Tityus serrulatus
(Universidade Federal de Minas GeraisUFMG, 2005-02-24)
Scorpion venom is a rich source of biologically active peptides that act in different systems, such as nervous and cardiovascular. A new structural family of peptides was found in the venom of the Brazilian yellow scorpion ...
Pharmacokinetics and pharmacodynamics of the glucagon-like peptide-1 analog liraglutide in healthy cats
(Elsevier B.V., 2015-04-01)
Glucagon-like peptide-1 (GLP-1) is an intestinal hormone that induces glucose-dependent stimulation of insulin secretion while suppressing glucagon secretion. Glucagon-like peptide-1 also increases beta cell mass and ...
Biological activity of antibacterial peptides matches synergism between electrostatic and non electrostatic forces
(Elsevier Science, 2014-07)
Substitution of Ala 108 and Ala 111 in the 107–115 human lysozyme (hLz) fragment results in a 20- fold increased anti-staphylococcal activity while its hemolytic activity becomes significant (30%) at very high concentrations. ...