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Conduto de orientação nervosa funcionalizado com células estromais mesenquimais multipotentes promove a regeneração do nervo isquiático em ratos
(Universidade Estadual Paulista (Unesp), 2020-10-19)
As lesões traumáticas do sistema nervoso periférico (SNP) são altamente debilitantes, levando a déficits sensório-motores a longo prazo. A regeneração nervosa depende de um microambiente permissivo para o crescimento axonal, ...
Regulación del receptor NMDA sináptico por la neurotrofina BDNF
(Universisdad de Chile, 2008)
La neurotrofina BDNF cumple un papel esencial en fenómenos que van desde
plasticidad sináptica implicada en memoria y aprendizaje hasta epilepsia. El exceso de
BDNF subyace a la fisiopatológia de la epilepsia del lobulo ...
Mesenchymal stem cells engrafted in a fibrin scaffold stimulate Schwann cell reactivity and axonal regeneration following sciatic nerve tubulization
(Elsevier B.V., 2015-03-01)
The present study investigated the effectiveness of mesenchymal stem cells (MSCs) associated with a fibrin scaffold (FS) for the peripheral regenerative process after nerve tubulization. Adult female Lewis rats received a ...
3D-printed nerve guidance conduits multi-functionalized with canine multipotent mesenchymal stromal cells promote neuroregeneration after sciatic nerve injury in rats
(2021-12-01)
Background: Nerve injuries are debilitating, leading to long-term motor deficits. Remyelination and axonal growth are supported and enhanced by growth factor and cytokines. Combination of nerve guidance conduits (NGCs) ...
Cardiac autonomic denervation and expression of neurotrophins (ngf and bdnf) and their receptors during experimental chagas disease
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE MORFOLOGIAUFMG, 2017)
Embora a disautonomia cardíaca seja uma característica distintiva da doença de Chagas, seu significado clínico e funcional ainda é especulado. Fatores neurotróficos estão potencialmente envolvidos; entretanto, estudos sobre ...
Schwann-like macroglia in adult rat brain
(2000)
Olfactory ensheathing cells (OECs) share properties with astrocytes and Schwann cells. This study was designed to test the hypothesis that glia with properties similar to those exhibited by OECs might be present in brain ...