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Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation
(Nature, 2018)
Background: Periodontal pathogens have been linked to oral and gastrointestinal (orodigestive) carcinogenesis. However, the
exact mechanisms remain unknown. Treponema denticola (Td) is associated with severe periodontitis, ...
The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide
(Elsevier Gmbh, Urban & Fischer Verlag, 2011-07-01)
The medium-term tongue carcinogenesis assay is a useful model for studying oral squamous cell carcinomas phase by phase. The aim of the present study was to investigate the expression of p53 by immunohistochemistry and ...
The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide
(Elsevier Gmbh, Urban & Fischer Verlag, 2011-07-01)
The medium-term tongue carcinogenesis assay is a useful model for studying oral squamous cell carcinomas phase by phase. The aim of the present study was to investigate the expression of p53 by immunohistochemistry and ...
Protective effects of yacon (Smallanthus sonchifolius) intake on experimental colon carcinogenesis
(Pergamon-Elsevier B.V. Ltd, 2014)
Optimization of the classical oral cancerization protocol in hamster to study oral cancer therapyOptimization of the classical oral cancerization protocol in hamster to study oral cancer therapy
(Wiley Blackwell Publishing, IncWiley Blackwell Publishing, Inc, 2020-09)
Objective(s): The hamster carcinogenesis model recapitulates oral oncogenesis. Dimethylbenz[a]anthracene (DMBA) cancerization induces early severe mucositis, affecting animal's welfare and causing tissue loss and pouch ...
Expressão imunohistoquímica de moléculas HLA não clássicas (HLA-G E HLA-E) e receptores CD4, CD28 em lesões de mucosa oral, associada a infecção pelo papilomavírus humano (HPV)
(Universidade Estadual Paulista (Unesp), 2006-12-13)
As células tumorais infectadas pelo HPV podem apresentar estratégias para escapar da resposta imunológica resultando na persistência da infecção viral e na transformação celular maligna. O objetivo do presente estudo foi ...