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Abnormal function of monoamine oxidase-A in comorbid major depressive disorder and cardiovascular disease: Pathophysiological and therapeutic implications (Review)
(SPANDIDOS PUBL LTDATHENS, 2012)
The association between major depressive disorder (MDD) and cardiovascular disease (CVD) is among the best described medical comorbidities. The presence of MDD increases the risk of cardiac admissions and mortality and ...
Avaliação do potencial efeito antidepressivo do 2-BFI, ligante imidazolínico I2, em camundongos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2012-03-02)
Depression is a complex, chronic and disabling psychiatric disease that carries
a high social cost. Among the various classes of antidepressants are the monoamine
oxidase A (MAO-A) inhibitors that reduce monoamine ...
Envolvimento dos sistemas serotoninérgico e dopaminérgico na ação do tipo antidepressiva do 7-flúor-1,3 difenilisoquinolina-1-amino em camundongos
(Universidade Federal de Santa MariaBRBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica, 2014-03-11)
Depression is a psychiatric disorder associated with a negative impact on quality of life. Monoaminergic system has been involved in this disease and in the action of antidepressants. This study aimed to investigate the ...
Neurotoxicity of some MAO Inhibitors in Adult Rat Hypothalamic Cell Culture
(Taylor & Francis Ltd, 2001-05-04)
Monoamine oxidase-A (MAO-A) (amiflamine (AMF)
and 4-methylthioamphetamine (MTA)) and MAO-B (Ldeprenyl)
inhibitors were found to be cytotoxic in a
concentration-dependent manner for RCHTcells derived
from adult rat ...
Sulfur-substituted α-alkyl phenethylamines as selective and reversible MAO-A inhibitors: Biological activities, CoMFA analysis, and active site modeling
(2005)
A series of phenethylamine derivatives with various ring substituents and with or without N-methyl and/or C-alpha methyl or ethyl groups was synthesized and assayed for their ability reversibly to inhibit monoamine oxidase ...