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Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia
(Springer Verlag (Germany), 2018)
Synthesis and antitumor evaluation of 8-phenylaminopyrimido[4,5-c]isoquinolinequinones
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
A series of 8-phenylaminopyrimido[4,5-c]isoquinoline-7,10-quinone derivatives were prepared by regioselective amination reaction of pyrimido[4,5-c] isoquinoline-7,10-quinones with arylamines in the presence of a Lewis acid ...
Cytotoxicity in patients with different clinical forms of Chagas disease
(1996)
There are few studies on cell-mediated cytotoxicity in human Chagas' disease. In the present study, we evaluated peripheral blood mononuclear cell (PBMC) cytotoxicity activity from chagasic patients with different clinical ...
Nitric oxide-releasing nanoparticles: synthesis, characterization, and cytotoxicity to tumorigenic cells
(Springer, 2017)
Nitric oxide (NO) is involved in several biological processes, including toxicity against tumor cells. The aim of this study was to synthesize, characterize, and evaluate the cytotoxicity of NO-releasing chitosan nanoparticles. ...
Efeito da melatonina na proteção contra estresse oxidativo induzido em células eritróides K562
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotecCâmpus São Carlos, 2020-03-06)
Erythrocytes are anucleated cells that play an extremely important role, since they participate in the transport of oxygen (O2) to tissues. Changes in the structure or functioning of the erythrocyte can lead to several ...
Correlação entre a produção de espécies reativas de oxigênio e a expressão da Timet oligopeptidase em células de leucemia com resistência a múltiplas drogas. Possíveis implicações para a via de apresentação de antígenos pelo MHC I
(Universidade Federal de São Paulo (UNIFESP), 2021)
Thimet oligopeptidase (THOP, endopeptidase EC 3.4.24.15) is a cytosolic metallopeptidase known to regulate the fate of post-proteasomal peptides, taking part of the antigen selection in the MHC class I presentation route. ...
Localization of myosin-Va in subpopulations of cells in rat endocrine organs
(SPRINGER, 2008)
Myosin-Va is a Ca2+/calmodulin-regulated unconventional myosin involved in the transport of vesicles, membranous organelles, and macromolecular complexes composed of proteins and mRNA. The cellular localization of myosin-Va ...
Studies of natural-killer-cells in pregnancy-induced hypertension
(Associação Brasileira de Divulgação Científica (ABRADIC), 1995-06-01)
The number and activity of natural killer (NK) cells were studied in 20 patients with pregnancy-induced hypertension (PIH), 15 uncomplicated pregnant women and 16 healthy non-pregnant women, All the pregnant women were ...
Studies of natural-killer-cells in pregnancy-induced hypertension
(Associação Brasileira de Divulgação Científica (ABRADIC), 1995-06-01)
The number and activity of natural killer (NK) cells were studied in 20 patients with pregnancy-induced hypertension (PIH), 15 uncomplicated pregnant women and 16 healthy non-pregnant women, All the pregnant women were ...