Buscar
Mostrando ítems 61-70 de 292
Induced pluripotent stem cell-derived neural precursors improve memory, synaptic and pathological abnormalities in a mouse model of Alzheimer’s disease
(MDPI, 2021)
Alzheimer's disease (AD) is the most common type of dementia in the elderly population. The disease is characterized by progressive memory loss, cerebral atrophy, extensive neuronal loss, synaptic alterations, brain ...
Graphene Oxide Sheets-based Platform For Induced Pluripotent Stem Cells Culture: Toxicity, Adherence, Growth And Application
(IOP PUBLISHING LTDBRISTOL, 2015)
Pluripotent Reprogramming of Fibroblasts by Lentiviralmediated Insertion of SOX2, C-MYC, and TCL-1A
(MARY ANN LIEBERT INC, 2011)
Reprogramming of somatic cells to pluripotency promises to boost cellular therapy. Most instances of direct reprogramming have been achieved by forced expression of defined exogenous factors using multiple viral vectors. ...
PROPOSALS FOR EMBRYONIC STEM CELL PRODUCTION WITHOUT DESTROYING HUMAN EMBRYOS: SCIENTIFIC AND BIOETHICAL CHALLENGES
(Centro Interdisciplinario de Estudios en Bioética, Universidad de Chile, 2009)
Altered neuronal network and rescue in a human MECP2 duplication model
(Nature Publishing Group Specialist Journals, 2016)
High RAC3 expression levels are required for induction and maintaining of cancer cell stemness
(Impact Journals, 2017-12)
RAC3 is a transcription coactivator, usually overexpressed in several tumors and required to maintain the pluripotency in normal stem cells. In this work we studied the association between RAC3 overexpression on cancer ...
A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells
(Cell Press, 2017)
Sickle cell anemia affects millions of people worldwide and is an emerging global health burden. As part of a large NIH-funded NextGen Consortium, we generated a diverse, comprehensive, and fully characterized library of ...